Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 18/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16864397 | 0.90 | QPCT (0.48) | QPCTTP53 | |
| SCHEMBL29410480 | 0.88 | QPCT (0.60) | QPCT | |
| SCHEMBL1444481 | 0.88 | QPCT (0.60) | QPCT | |
| SCHEMBL16864406 | 0.83 | QPCT (0.43) | QPCT | |
| SCHEMBL12819253 | 0.83 | QPCT (0.68) | QPCTTP53MAPTSMN1; SMN2 | |
| SCHEMBL12819597 | 0.83 | QPCT (0.68) | QPCTTP53MAPTSMN1; SMN2 | |
| SCHEMBL12814445 | 0.81 | QPCT (0.57) | QPCTTP53SMN1; SMN2 | |
| SCHEMBL1444692 | 0.77 | QPCT (0.60) | QPCTTP53SMN1; SMN2 | |
| SCHEMBL1444480 | 0.77 | QPCT (0.60) | QPCTTP53SMN1; SMN2 | |
| SCHEMBL29410482 | 0.77 | QPCT (0.60) | QPCTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2475428-B1 | HETEROCYLCIC DERIVATIVES AS INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2015-07-01 | — | — | EP | disclosed |