Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL1687038 | 1.00 | — | — | |
| Iodide SCHEMBL10455838 | 1.00 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Iodide SCHEMBL8148784 | 0.96 | — | — | |
| Fluoride Ion SCHEMBL8150351 | 0.93 | — | — | |
| SCHEMBL11589353 | 0.93 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Bromide SCHEMBL1686435 | 0.93 | — | — | |
| Fluoride Ion SCHEMBL11773900 | 0.93 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6563754 | 0.93 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL10520281 | 0.93 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL151384 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1680394-B | Process for producing compound, catalyst component, process for producing catalyst, and process for producing addition polymer | SUMITOMO CO LTD | 2012-11-21 | — | — | CN | disclosed |
| US-7932330-B2 | Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-04-26 | — | — | US | disclosed |
| US-7592402-B2 | Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-09-22 | — | — | US | disclosed |
| US-7524789-B2 | Process for producing modified particle, carrier or catalyst component for addition polymerization, pre-polymerized catalyst component therefor, catalyst therefor, and addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-04-28 | — | — | US | disclosed |
| US-20080319148-A1 | Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED | 2008-12-25 | — | — | US | disclosed |
| US-7122691-B2 | Process for producing compound, catalyst component for addition polymerization, process for producing catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-17 | — | — | US | disclosed |
| US-20050245701-A1 | Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED | 2005-11-03 | — | — | US | disclosed |
| CN-1680394-A | Process for producing compound, catalyst component, process for producing catalyst, and process for producing addition polymer | SUMITOMO CHEMICAL CO (JP) | 2005-10-12 | — | — | CN | disclosed |
| US-20050222351-A1 | Process for producing compound, catalyst component for addition polymerization, process for producing catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED | 2005-10-06 | — | — | US | disclosed |
| US-20050148459-A1 | Process for producing modified particle, carrier or catalyst component for addition polymerization, pre-polymerized catalyst component therefor, catalyst therefor, and addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED | 2005-07-07 | — | — | US | disclosed |
| US-5171776-A | Crosslinked polymer of dicyclopentadiene produced by metathesis polymerization; adjust heat deflection and glass transition temperature | HERCULES INCORPORATED (US) | 1992-12-15 | — | — | US | disclosed |
| US-5055499-A | Metathesis polymerizing a cyclolefin in the presence of a filler treated with a norbornene-substituted silane coupling agent; boat and automobile reaction injection molded parts; rigidity; impact strength | HERCULES INCORPORATED (US) | 1991-10-08 | — | — | US | disclosed |
| EP-0439650-A1 | Molded polymer article filled with inorganic material and production of said article | HERCULES INCORPORATED (US) | 1991-08-07 | — | — | EP | disclosed |
| EP-0329063-A2 | Process for producing a colored molded article of metathesis polymerized polymer | HERCULES INCORPORATED (US) | 1989-08-23 | — | — | EP | disclosed |
| EP-0305933-A2 | Process for producing a molded article of metathesis polymerized polymer | HERCULES INCORPORATED (US) | 1989-03-08 | — | — | EP | disclosed |
| US-4066683-A | PROCESS FOR THE PREPARATION OF DIAMINOMALEONITRILE | NIPPON CHEMICALS CO., LTD. (JA) | 1978-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222351-A1 | Process for producing compound, catalyst component for addition polymerization, process for producing catalyst for addition polymerization, and process for producing addition polymer | CCNT1, C5, C9 | TSHR 4243/4885THRB 3963/4885DNM1 3564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.