Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.50 |
| ▸ | CYP4Z1 | Q86W10 | 3/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.46 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.46 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16865355 | 1.00 | SPHK1 (0.50) | SPHK1CYP4Z1SPHK2CYP4F11CYP4F12 | |
| SCHEMBL16865352 | 0.83 | CYP2C9 (0.45) | CYP4F2CYP4A11ALDH1A1HPGDKDM4E | |
| SCHEMBL16865348 | 0.83 | CYP2C9 (0.45) | CYP4F2CYP4A11ALDH1A1HPGDKDM4E | |
| SCHEMBL16865329 | 0.81 | NOS3 (0.45) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL16865353 | 0.81 | NOS3 (0.45) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL16859612 | 0.81 | NOS3 (0.45) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL16865346 | 0.80 | MEN1 (0.49) | CYP4F2CYP4A11ALDH1A1HPGDKDM4E | |
| SCHEMBL16865347 | 0.80 | MEN1 (0.49) | CYP4F2CYP4A11ALDH1A1HPGDKDM4E | |
| SCHEMBL6286441 | 0.77 | CYP4F2 (0.72) | CYP4Z1CYP4F11CYP4F12CYP4F2CYP4A11 | |
| SCHEMBL9997959 | 0.75 | SPHK1 (0.51) | SPHK1SPHK2ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133488-B2 | Synthetic methods and compounds related thereto | UNIVERSITY OF ALASKA FAIRBANKS (US) | 2015-09-15 | — | — | US | disclosed |
| US-9133488-B2 | Synthetic methods and compounds related thereto | UNIVERSITY OF ALASKA FAIRBANKS (US) | 2015-09-15 | — | — | US | disclosed |
| US-20150184206-A1 | SYNTHETIC METHODS AND COMPOUNDS RELATED THERETO | UNIVERSITY OF ALASKA FAIRBANKS | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150184206-A1 | SYNTHETIC METHODS AND COMPOUNDS RELATED THERETO | LSS, CYP51A1, FASN | SPHK1 429/4885CYP4Z1 245/4885SPHK2 653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.