Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16865369 | 1.00 | HDAC6 (0.34) | HDAC6HDAC1HDAC2CYP2D6CA1 | |
| SCHEMBL16865374 | 1.00 | HDAC6 (0.34) | HDAC6HDAC1HDAC2CYP2D6CA1 | |
| SCHEMBL5567395 | 0.88 | CA1 (0.35) | HDAC6HDAC1HDAC2CYP2D6CA1 | |
| SCHEMBL5567390 | 0.88 | CA1 (0.35) | HDAC6HDAC1HDAC2CYP2D6CA1 | |
| SCHEMBL5565242 | 0.81 | CTSS (0.35) | HDAC6HDAC1HDAC2CA1CA2 | |
| SCHEMBL5565245 | 0.81 | CTSS (0.35) | HDAC6HDAC1HDAC2CA1CA2 | |
| SCHEMBL18055171 | 0.78 | HDAC6 (0.35) | HDAC6HDAC1HDAC2CYP2D6CA1 | |
| SCHEMBL5565289 | 0.77 | AAK1 (0.35) | HDAC6HDAC1HDAC2CYP2D6CA1 | |
| SCHEMBL86238 | 0.77 | AAK1 (0.35) | HDAC6HDAC1HDAC2CYP2D6CA1 | |
| SCHEMBL25536966 | 0.77 | AAK1 (0.35) | HDAC6HDAC1HDAC2CYP2D6CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133488-B2 | Synthetic methods and compounds related thereto | UNIVERSITY OF ALASKA FAIRBANKS (US) | 2015-09-15 | — | — | US | disclosed |
| US-20150184206-A1 | SYNTHETIC METHODS AND COMPOUNDS RELATED THERETO | UNIVERSITY OF ALASKA FAIRBANKS | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150184206-A1 | SYNTHETIC METHODS AND COMPOUNDS RELATED THERETO | LSS, CYP51A1, FASN | HDAC6 2378/4885HDAC1 1492/4885HDAC2 962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.