SCHEMBL16865386

SCHEMBL16865386

O=C1N(Cc2ccccc2)C(=O)C(Cl)(Cc2ccccc2)C(=O)N1c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 7/20 0.51
NPSR1 Q6W5P4 1/20 0.51
CTSG P08311 2/20 0.47
F2 P00734 1/20 0.47
PLG P00747 1/20 0.47
CMA1 P23946 1/20 0.47
CTRC Q99895 1/20 0.47
GSK3A P49840 1/20 0.41
GSK3B P49841 1/20 0.41
MGLL Q99685 1/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
THPO P40225 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
PRTN3 P24158 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17716265 0.81 ELANE (0.72) ELANENPSR1CTSGF2PLG
SCHEMBL16865411 0.81 ELANE (0.50) ELANENPSR1CTSGF2PLG
SCHEMBL16865413 0.81 ELANE (0.50) ELANENPSR1CTSGF2PLG
SCHEMBL16865410 0.76 ELANE (0.51) ELANEMGLLALDH1A1CYP1A2CYP3A4
SCHEMBL16865412 0.75 SCN9A (0.53) ELANENPSR1CTSGF2PLG
SCHEMBL16865419 0.75 NPSR1 (0.54) ELANENPSR1CTSGF2PLG
SCHEMBL16865447 0.75 ELANE (0.47) ELANENPSR1CTSGF2PLG
SCHEMBL16865426 0.75 ELANE (0.44) ELANENPSR1CTSGF2PLG
SCHEMBL4428745 0.74 ELANE (0.74) ELANENPSR1CTSGF2PLG
SCHEMBL17716262 0.74 NPSR1 (0.74) ELANENPSR1CTSGF2PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND C1R, C1S, C3AR1 ELANE 2715/4885NPSR1 2710/4885CTSG 2463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.