SCHEMBL16865392

SCHEMBL16865392

O=C1NC(=O)C(O)(c2ccccc2)C(=O)N1Cc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.61
SCN9A Q15858 2/20 0.53
P2RX1 P51575 1/20 0.53
P2RX3 P56373 1/20 0.53
P2RX4 Q99571 1/20 0.53
P2RX7 Q99572 1/20 0.53
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
ELANE P08246 3/20 0.47
CNR1 P21554 1/20 0.47
F2 P00734 1/20 0.46
PLG P00747 1/20 0.46
CTSG P08311 1/20 0.46
CMA1 P23946 1/20 0.46
CTRC Q99895 1/20 0.46
TP53 P04637 1/20 0.45
HDAC6 Q9UBN7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17716267 0.81 CYP2C19 (0.65) CYP2C19KMT2AMEN1ELANECNR1
SCHEMBL16865430 0.79 CYP2C19 (0.58) CYP2C19KMT2AMEN1ELANECNR1
SCHEMBL16865384 0.79 CYP2C19 (0.62) CYP2C19KMT2AMEN1ELANECNR1
SCHEMBL5268591 0.78 CYP2C19 (0.74) CYP2C19KMT2AMEN1ELANECNR1
SCHEMBL16865434 0.78 CYP2C19 (0.57) CYP2C19KMT2AMEN1ELANECNR1
SCHEMBL5656508 0.77 SCN9A (0.84) SCN9AP2RX1P2RX3P2RX4P2RX7
SCHEMBL28992834 0.77 SCN9A (0.84) SCN9AP2RX1P2RX3P2RX4P2RX7
SCHEMBL16268124 0.76 CYP2C19 (1.00) CYP2C19KMT2AMEN1ELANECNR1
SCHEMBL7833789 0.76 ELANE (0.71) CYP2C19KMT2AMEN1ELANECNR1
SCHEMBL17716268 0.76 CYP2C19 (0.57) CYP2C19KMT2AMEN1ELANECNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND C1R, C1S, C3AR1 CYP2C19 1712/4885SCN9A 3453/4885P2RX1 4368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.