Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 4/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | CTSG | P08311 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | CTRC | Q99895 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GSK3A | P49840 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16268124 | 0.85 | CYP2C19 (1.00) | CYP2C19KMT2AMEN1ELANECNR1 | |
| SCHEMBL16865384 | 0.79 | CYP2C19 (0.62) | CYP2C19KMT2AMEN1ELANECNR1 | |
| SCHEMBL16865392 | 0.78 | CYP2C19 (0.61) | CYP2C19KMT2AMEN1ELANECNR1 | |
| SCHEMBL17716267 | 0.78 | CYP2C19 (0.65) | CYP2C19KMT2AMEN1ELANECNR1 | |
| SCHEMBL7833789 | 0.76 | ELANE (0.71) | CYP2C19KMT2AMEN1ELANECNR1 | |
| SCHEMBL17716268 | 0.76 | CYP2C19 (0.57) | CYP2C19KMT2AMEN1ELANECNR1 | |
| SCHEMBL27630388 | 0.73 | ELANE (0.73) | CYP2C19KMT2AMEN1ELANECNR1 | |
| SCHEMBL16865430 | 0.73 | CYP2C19 (0.58) | CYP2C19KMT2AMEN1ELANECNR1 | |
| SCHEMBL16865390 | 0.73 | CYP2C19 (0.58) | CYP2C19KMT2AMEN1ELANECNR1 | |
| SCHEMBL15461433 | 0.72 | CNR1 (0.80) | CYP2C19KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1459726-B1 | ADHESIVES FOR DENTAL USE | TOKUYAMA CORP (JP) | 2013-10-02 | — | — | EP | disclosed |
| EP-1431315-B1 | Photopolymerization initiator and photopolymerizable composition | TOKUYAMA CORP (JP) | 2007-10-17 | — | — | EP | disclosed |
| US-7041714-B2 | Dental adhesive | TOKUYAMA CORPORATION (JP) | 2006-05-09 | — | — | US | disclosed |
| US-20040186195-A1 | Photopolymerization initiator and photopolymerizable composition | TOKUYAMA CORPORATION (JP) | 2004-09-23 | — | — | US | disclosed |
| EP-1459726-A1 | ADHESIVES FOR DENTAL USE | TOKUYAMA CORPORATION (JP) | 2004-09-22 | — | — | EP | disclosed |
| EP-1431315-A2 | Photopolymerization initiator and photopolymerizable composition | Tokuyama Corporation (JP) | 2004-06-23 | — | — | EP | disclosed |
| US-20040077746-A1 | Adhesives for dental use | TOKUYAMA CORPORATION (JP) | 2004-04-22 | — | — | US | disclosed |
| US-5290172-A | Method for preparing a tooth surface for bonding | GC CORPORATION (JP) | 1994-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077746-A1 | Adhesives for dental use | ICAM1, CDH1, VCAM1 | CYP2C19 2534/4885KMT2A 560/4885MEN1 4143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.