SCHEMBL1686752

SCHEMBL1686752

CC(C)c1ccccc1[Si](O)(O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.50
GABRB2 P47870 2/20 0.50
GABRG2 P18507 2/20 0.46
GABRB3 P28472 2/20 0.46
LMNA P02545 2/20 0.46
TSHR P16473 2/20 0.46
FAAH O00519 2/20 0.46
CYP3A4 P08684 2/20 0.46
GABRB1 P18505 2/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CYP1A2 P05177 1/20 0.46
HPGD P15428 1/20 0.46
PTGS1 P23219 1/20 0.46
SLC6A2 P23975 1/20 0.46
HTR2C P28335 1/20 0.46
GABRA5 P31644 1/20 0.46
GABRA3 P34903 1/20 0.46
HTR2B P41595 1/20 0.46
GABRA2 P47869 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1686644 0.86 GABRA1 (0.50) GABRA1GABRB2GABRG2GABRB3LMNA
SCHEMBL1686819 0.79 TSHR (0.59) GABRA1GABRB2LMNATSHRL3MBTL1
SCHEMBL8419390 0.76 GABRA1 (0.44) GABRA1GABRB2GABRG2GABRB3LMNA
SCHEMBL8421031 0.76 GABRA1 (0.44) GABRA1GABRB2GABRG2GABRB3LMNA
SCHEMBL8423080 0.76 GABRA1 (0.44) GABRA1GABRB2GABRG2GABRB3LMNA
SCHEMBL20815386 0.74 GABRA1 (0.43) GABRA1GABRB2GABRG2GABRB3LMNA
SCHEMBL3153921 0.74 GABRA1 (0.43) GABRA1GABRB2GABRG2GABRB3LMNA
Hydrogen Peroxide SCHEMBL99126 0.73 GABRA1 (0.65) GABRA1GABRB2GABRG2GABRB3LMNA
Hydrogen Peroxide SCHEMBL35519 0.73 GABRA1 (0.65) GABRA1GABRB2GABRG2GABRB3LMNA
Hydrogen Peroxide SCHEMBL30120583 0.73 GABRA1 (0.65) GABRA1GABRB2GABRG2GABRB3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7932330-B2 Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-26 US disclosed
US-7592402-B2 Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-09-22 US disclosed
US-20080319148-A1 Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2008-12-25 US disclosed
US-7115539-B2 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2006-10-03 US disclosed
US-20050245701-A1 Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2005-11-03 US disclosed
US-20040209762-A1 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2004-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040209762-A1 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer AP1M1, PYM1, SEM1 GABRA1 4006/4885GABRB2 4485/4885GABRG2 4198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.