SCHEMBL1686941

SCHEMBL1686941

Cc1ccc([Si](O)(O)c2ccc(C)cc2C)c(C)c1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.48
TP53 P04637 1/20 0.48
TRPA1 O75762 1/20 0.39
CYP1A2 P05177 2/20 0.38
CYP2A6 P11509 2/20 0.38
ALDH1A1 P00352 4/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
RAB9A P51151 2/20 0.36
NPC1 O15118 1/20 0.36
RAPGEF4 Q8WZA2 2/20 0.35
GAA P10253 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MAPT P10636 3/20 0.34
KDM4E B2RXH2 2/20 0.34
LMNA P02545 1/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
GBA1 P04062 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1686578 0.85 TDP1 (0.48) TDP1TP53TRPA1CYP1A2CYP2A6
SCHEMBL1686690 0.80 ALDH1A1 (0.42) TDP1TP53TRPA1CYP1A2CYP2A6
SCHEMBL28033237 0.77 TDP1 (0.44) TDP1TP53TRPA1CYP1A2CYP2A6
SCHEMBL1317920 0.75 TDP1 (0.42) TDP1TP53TRPA1CYP1A2CYP2A6
SCHEMBL5708414 0.75 TDP1 (0.42) TDP1TP53TRPA1CYP1A2CYP2A6
SCHEMBL7778417 0.75 TDP1 (0.42) TDP1TP53TRPA1CYP1A2CYP2A6
SCHEMBL16707374 0.75 TDP1 (0.42) TDP1TP53TRPA1CYP1A2CYP2A6
SCHEMBL1992127 0.75 TDP1 (0.42) TDP1TP53CYP1A2CYP2A6ALDH1A1
SCHEMBL1317064 0.73 TDP1 (0.41) TDP1TP53TRPA1CYP1A2CYP2A6
SCHEMBL1314725 0.73 TDP1 (0.41) TDP1TP53TRPA1CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2805999-A1 Photosensitive Alkali-Soluble Silicone Resin Composition Asahi Kasei E-materials Corporation (JP) 2014-11-26 EP disclosed
US-20140193632-A1 PHOTOSENSITIVE ALKALI-SOLUBLE SILICONE RESIN COMPOSITION ASAHI KASEI E-MATERIALS CORPORATION (JP) 2014-07-10 US disclosed
EP-2752712-A1 PHOTOSENSITIVE ALKALI-SOLUBLE SILICONE RESIN COMPOSITION Asahi Kasei E-Materials Corporation (JP) 2014-07-09 EP disclosed
US-7932330-B2 Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-26 US disclosed
US-7592402-B2 Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-09-22 US disclosed
US-20080319148-A1 Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2008-12-25 US disclosed
US-7115539-B2 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2006-10-03 US disclosed
US-20050245701-A1 Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2005-11-03 US disclosed
US-20040209762-A1 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2004-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040209762-A1 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer AP1M1, PYM1, SEM1 TDP1 3299/4885TP53 4741/4885TRPA1 2970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.