Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 4/20 | 0.59 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.53 |
| ▸ | TUBB | P07437 | 6/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | LYN | P07948 | 1/20 | 0.53 |
| ▸ | BCR | P11274 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254717 | 0.97 | SRC (0.60) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL254176 | 0.94 | SRC (0.66) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16870760 | 0.94 | SRC (0.59) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10168908 | 0.91 | SRC (0.60) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL254926 | 0.90 | SRC (0.59) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL255179 | 0.89 | SRC (0.72) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10297922 | 0.89 | TUBB4A (0.55) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL254567 | 0.88 | SRC (0.66) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL254404 | 0.88 | SRC (0.57) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL258009 | 0.88 | SRC (0.65) | SRCTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9655903-B2 | Compositions and methods of treating cell proliferation disorders | ATHENEX, INC. (US) | 2017-05-23 | — | — | US | disclosed |
| US-20150182532-A1 | COMPOSITIONS AND METHODS OF TREATING CELL PROLIFERATION DISORDERS | SAGARD HEALTHCARE ROYALTY PARTNERS, LP, AS ADMINISTRATIVE AGENT (CA) | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150182532-A1 | COMPOSITIONS AND METHODS OF TREATING CELL PROLIFERATION DISORDERS | MKI67, CCNC, CCNA1 | SRC 430/4885TUBB4A 218/4885TUBB 342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.