SCHEMBL16870869

SCHEMBL16870869

Cc1ccc(Nc2ncc(C3CCCN3C(=O)c3nccs3)cc2Cl)cn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16870868 0.80 GRM5 (0.66) GRM5
SCHEMBL990302 0.80 GRM5 (0.71) GRM5
SCHEMBL991465 0.77 GRM5 (0.75) GRM5
SCHEMBL992193 0.77 GRM5 (0.72) GRM5
SCHEMBL990849 0.77 GRM5 (0.69) GRM5
SCHEMBL990397 0.76 GRM5 (0.68) GRM5
SCHEMBL4529136 0.74 GRM5 (0.59) GRM5
SCHEMBL990788 0.73 GRM5 (0.72) GRM5
SCHEMBL16870860 0.73 GRM5 (1.00) GRM5
SCHEMBL16870876 0.73 GRM5 (1.00) GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015098991-A1 N-ALKYLAMIDE DERIVATIVE AND MEDICINAL USE THEREOF 東レ株式会社 2015-07-02 WO disclosed