Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 10/20 | 0.66 |
| ▸ | CCNC | P24863 | 9/20 | 0.45 |
| ▸ | CDK8 | P49336 | 9/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16870869 | 0.80 | GRM5 (1.00) | GRM5 | |
| SCHEMBL28177282 | 0.72 | GAA (0.49) | GRM5SCD5 | |
| SCHEMBL28284253 | 0.72 | GAA (0.49) | GRM5SCD5 | |
| SCHEMBL23504274 | 0.69 | GRM5 (1.00) | GRM5 | |
| SCHEMBL16870913 | 0.69 | GRM5 (1.00) | GRM5 | |
| SCHEMBL3453680 | 0.69 | — | — | |
| SCHEMBL7481526 | 0.68 | GRM5 (0.36) | GRM5CCNCCDK8DRD2GSK3A | |
| SCHEMBL28284252 | 0.68 | HPGD (0.55) | GRM5 | |
| SCHEMBL7098848 | 0.68 | GRM5 (0.37) | GRM5 | |
| SCHEMBL7955425 | 0.67 | TDP1 (0.45) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015098991-A1 | N-ALKYLAMIDE DERIVATIVE AND MEDICINAL USE THEREOF | 東レ株式会社 | 2015-07-02 | — | — | WO | disclosed |