Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16871005 | 0.84 | BCHE (0.35) | GSK3BALDH1A1KMT2ABCHEACHE | |
| SCHEMBL16871014 | 0.83 | MCHR1 (0.44) | ALDH1A1POLBBCHESMN1; SMN2 | |
| SCHEMBL9433695 | 0.73 | GSK3B (0.43) | GSK3BPOLBKMT2AMEN1 | |
| SCHEMBL11073006 | 0.73 | BCHE (0.41) | GSK3BALDH1A1KMT2ABCHEACHE | |
| SCHEMBL29222316 | 0.72 | GSK3B (0.37) | GSK3BPOLBKMT2AMEN1 | |
| SCHEMBL28691443 | 0.71 | GSK3B (0.37) | GSK3BPOLBKMT2AMEN1 | |
| SCHEMBL7547859 | 0.70 | FNTA (0.41) | GSK3BPOLBKMT2ABCHEMEN1 | |
| SCHEMBL8015168 | 0.69 | PPARG (0.36) | GSK3BPOLBKMT2AMEN1PPARG | |
| SCHEMBL11355350 | 0.69 | KMT2A (0.35) | GSK3BALDH1A1POLBKMT2ALMNA | |
| SCHEMBL9743286 | 0.68 | GSK3B (0.42) | GSK3BPOLBKMT2ABCHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150183772-A1 | ALKYLATION OF AZOLES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2015-07-02 | — | — | US | disclosed |
| US-20150183772-A1 | ALKYLATION OF AZOLES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183772-A1 | ALKYLATION OF AZOLES | AKR1C3, DCXR, AKR1C2 | GSK3B 2988/4885HRH1 3563/4885ALDH1A1 877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.