Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009282 | 0.79 | PPARG (0.40) | PPARGKMT2AMEN1 | |
| SCHEMBL8008940 | 0.79 | PPARG (0.43) | PPARGGSK3BPOLB | |
| SCHEMBL9433695 | 0.78 | GSK3B (0.43) | GSK3BKMT2AMEN1POLB | |
| SCHEMBL29222316 | 0.76 | GSK3B (0.37) | GSK3BKMT2ACASP3MEN1POLB | |
| SCHEMBL8743157 | 0.76 | GSK3B (0.40) | GSK3BKMT2ACASP3MEN1POLB | |
| SCHEMBL28691443 | 0.73 | GSK3B (0.37) | GSK3BKMT2ACASP3MEN1POLB | |
| SCHEMBL8011340 | 0.72 | MEN1 (0.43) | PPARGKMT2AMEN1 | |
| SCHEMBL11355350 | 0.70 | KMT2A (0.35) | GSK3BKMT2ACASP3MEN1POLB | |
| SCHEMBL16871129 | 0.69 | GSK3B (0.40) | PPARGGSK3BKMT2AMEN1POLB | |
| SCHEMBL7547863 | 0.64 | FNTA (0.41) | PPARGGSK3BKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000030632-A1 | ARYL AND HETEROARYL COMPOUNDS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS | EISAI CO., LTD. (JP) | 2000-06-02 | — | — | WO | claimed |
| WO-2000030632-A1 | ARYL AND HETEROARYL COMPOUNDS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS | EISAI CO., LTD. (JP) | 2000-06-02 | — | — | WO | disclosed |