Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | PRKACG | P22612 | 1/20 | 0.37 |
| ▸ | PRKACB | P22694 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.37 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.37 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31170931 | 0.77 | CDC25B (0.49) | KDM4ECDC25BNPSR1RXFP1PDE2A | |
| SCHEMBL824371 | 0.77 | CDC25B (0.49) | KDM4ECDC25BNPSR1RXFP1PDE2A | |
| SCHEMBL1687672 | 0.75 | SMARCA2 (0.39) | SMARCA2SMARCA4FEN1 | |
| SCHEMBL18934625 | 0.74 | KDM4E (0.38) | KDM4ENPSR1PDE2APDE6DPDE8A | |
| SCHEMBL1698065 | 0.70 | KDM4E (0.53) | KDM4ENPSR1ALDH1A1HPGDMAPT | |
| SCHEMBL31170879 | 0.69 | ADRA1A (0.32) | KDM4E | |
| SCHEMBL18463241 | 0.68 | AURKA (0.48) | KDM4ECDC25BPDE2APDE10AALDH1A1 | |
| SCHEMBL18463374 | 0.68 | AURKA (0.45) | KDM4ECDC25BALDH1A1HPGDMAPT | |
| SCHEMBL18934521 | 0.68 | KDM4E (0.44) | KDM4EALDH1A1HPGDMAPTPKM | |
| SCHEMBL18721297 | 0.67 | AURKA (0.49) | KDM4EPDE2APDE6DPDE8APDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9425409-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2016-08-23 | — | — | US | disclosed |
| US-9425409-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2016-08-23 | — | — | US | disclosed |
| US-20130207048-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) | 2013-08-15 | — | — | US | disclosed |
| US-20130207048-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) | 2013-08-15 | — | — | US | disclosed |
| WO-2012045384-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-04-12 | — | — | WO | disclosed |