Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 0.45 |
| ▸ | STS | P08842 | 13/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16879765 | 0.89 | CYP19A1 (0.40) | CYP19A1STS | |
| SCHEMBL16879688 | 0.86 | CYP19A1 (0.59) | CYP19A1STS | |
| SCHEMBL16879982 | 0.84 | PIM1 (0.44) | CYP19A1STS | |
| SCHEMBL16879703 | 0.83 | CYP19A1 (0.48) | CYP19A1STSCA1CA2CA9 | |
| SCHEMBL16879838 | 0.79 | CYP19A1 (0.46) | CYP19A1STS | |
| SCHEMBL16879450 | 0.78 | STS (0.40) | CYP19A1STSCA1CA2CA9 | |
| SCHEMBL16879691 | 0.78 | CYP19A1 (0.45) | CYP19A1STSCA1CA2CA9 | |
| SCHEMBL16879653 | 0.74 | POLB (0.31) | CYP19A1 | |
| SCHEMBL16880153 | 0.74 | CYP19A1 (0.45) | CYP19A1STSCA2 | |
| SCHEMBL16879757 | 0.73 | CYP19A1 (0.42) | CYP19A1STSCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3089966-A1 | NEW SUBSTITUTED BIPHENYL ANALOGUES AS DUAL INHIBITORS OF AROMATASE AND SULFATASE | Beaufour Ipsen Tianjin Pharmaceutical Co., Ltd (CN) | 2016-11-09 | — | — | EP | disclosed |
| WO-2015100609-A1 | NEW SUBSTITUTED BIPHENYL ANALOGUES AS DUAL INHIBITORS OF AROMATASE AND SULFATASE | BEAUFOUR IPSEN TIANJIN PHARMACEUTICAL CO., LTD (CN) | 2015-07-09 | — | — | WO | disclosed |