Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 20/20 | 0.46 |
| ▸ | STS | P08842 | 15/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16879688 | 0.88 | CYP19A1 (0.59) | CYP19A1STS | |
| SCHEMBL16879757 | 0.82 | CYP19A1 (0.42) | CYP19A1STS | |
| SCHEMBL16880153 | 0.81 | CYP19A1 (0.45) | CYP19A1STS | |
| SCHEMBL16879867 | 0.79 | STS (0.38) | CYP19A1STS | |
| SCHEMBL16879686 | 0.79 | CYP19A1 (0.45) | CYP19A1STS | |
| SCHEMBL16879703 | 0.78 | CYP19A1 (0.48) | CYP19A1STS | |
| SCHEMBL16879691 | 0.76 | CYP19A1 (0.45) | CYP19A1STS | |
| SCHEMBL16879760 | 0.74 | CYP19A1 (0.37) | CYP19A1STS | |
| SCHEMBL16879494 | 0.73 | CYP19A1 (0.57) | CYP19A1STS | |
| SCHEMBL16879495 | 0.73 | CYP19A1 (0.35) | CYP19A1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3089966-A1 | NEW SUBSTITUTED BIPHENYL ANALOGUES AS DUAL INHIBITORS OF AROMATASE AND SULFATASE | Beaufour Ipsen Tianjin Pharmaceutical Co., Ltd (CN) | 2016-11-09 | — | — | EP | disclosed |
| WO-2015100609-A1 | NEW SUBSTITUTED BIPHENYL ANALOGUES AS DUAL INHIBITORS OF AROMATASE AND SULFATASE | BEAUFOUR IPSEN TIANJIN PHARMACEUTICAL CO., LTD (CN) | 2015-07-09 | — | — | WO | disclosed |