Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | GLS | O94925 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16880569 | 0.87 | CYP2C9 (0.43) | NAMPTDYRK1AKDM4AKCNA5CYP3A4 | |
| SCHEMBL16881402 | 0.86 | NAMPT (0.45) | NAMPTDYRK1AKDM4AHDAC1CYP3A4 | |
| SCHEMBL510089 | 0.84 | DYRK1A (0.51) | NAMPTDYRK1AKDM4AHDAC1CYP3A4 | |
| SCHEMBL30159605 | 0.78 | KCNA5 (0.56) | NAMPTKDM4AHDAC1KCNA5HDAC10 | |
| SCHEMBL8018113 | 0.78 | KCNA5 (0.56) | NAMPTKDM4AHDAC1KCNA5HDAC10 | |
| SCHEMBL16881429 | 0.77 | KLKB1 (0.44) | NAMPTHDAC10HDAC6KLKB1KLK1 | |
| SCHEMBL16881353 | 0.75 | NAMPT (0.42) | NAMPTDYRK1ACYP3A4KLKB1KLK1 | |
| SCHEMBL6675519 | 0.74 | KDM4A (0.44) | NAMPTKDM4AHDAC1KCNA5HDAC10 | |
| SCHEMBL15862351 | 0.74 | EPHX2 (0.51) | NAMPTKDM4AHDAC1KCNA5HDAC10 | |
| SCHEMBL29376317 | 0.74 | DYRK1A (0.56) | NAMPTDYRK1AKDM4AHDAC1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3089746-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | Lifesci Pharmaceuticals, Inc. (BB) | 2016-11-09 | — | — | EP | disclosed |
| WO-2015103317-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2015-07-09 | — | — | WO | disclosed |