Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16881353 | 0.88 | NAMPT (0.42) | CYP2C9CYP2C19NAMPTP2RY12KMT2A | |
| SCHEMBL16881041 | 0.87 | NAMPT (0.43) | NAMPTKMT2AKDM4AKCNA5CYP3A4 | |
| SCHEMBL509278 | 0.86 | CYP2C19 (0.51) | CYP2C9CYP2C19NAMPTKMT2APOLB | |
| SCHEMBL18019821 | 0.75 | DYRK1A (0.50) | NAMPTKDM4ACYP3A4DYRK1AALDH1A1 | |
| SCHEMBL161804 | 0.75 | CYP2C9 (0.61) | CYP2C9CYP2C19NAMPTKMT2APOLB | |
| SCHEMBL16880823 | 0.75 | KLKB1 (0.44) | NAMPTCYP3A4DYRK1AKLKB1KLK1 | |
| SCHEMBL16881402 | 0.75 | NAMPT (0.45) | NAMPTKDM4ACYP3A4DYRK1ASCN2A | |
| SCHEMBL8018113 | 0.74 | KCNA5 (0.56) | NAMPTKMT2AKDM4APOLBGAA | |
| SCHEMBL30159605 | 0.74 | KCNA5 (0.56) | NAMPTKMT2AKDM4APOLBGAA | |
| SCHEMBL16881199 | 0.74 | CYP2C9 (0.48) | CYP2C9CYP2C19P2RY12KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061480-B | Therapeutic inhibitory compounds | 莱福斯希医药公司 | 2020-02-28 | — | — | CN | disclosed |
| EP-3089746-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | Lifesci Pharmaceuticals, Inc. (BB) | 2016-11-09 | — | — | EP | disclosed |
| CN-106061480-A | Therapeutic inhibitory compounds | 莱福斯希医药公司 | 2016-10-26 | — | — | CN | disclosed |
| WO-2015103317-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2015-07-09 | — | — | WO | disclosed |