Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.54 |
| ▸ | SLC18A3 | Q16572 | 7/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980590 | 0.89 | HDAC1 (0.68) | HDAC1HDAC6HDAC8SIGMAR1SLC18A3 | |
| SCHEMBL13519235 | 0.87 | HDAC1 (0.69) | HDAC1HDAC6HDAC8SIGMAR1SLC18A3 | |
| SCHEMBL15494623 | 0.85 | HDAC1 (0.64) | HDAC1HDAC6HDAC8SIGMAR1SLC18A3 | |
| SCHEMBL15160327 | 0.85 | HDAC1 (0.67) | HDAC1HDAC6HDAC8SIGMAR1SLC18A3 | |
| SCHEMBL17117621 | 0.83 | HDAC1 (0.64) | HDAC1HDAC6HDAC8SIGMAR1SLC18A3 | |
| SCHEMBL13518796 | 0.83 | HDAC1 (0.78) | HDAC1HDAC6HDAC8SIGMAR1SLC18A3 | |
| SCHEMBL15158679 | 0.82 | HDAC1 (0.63) | HDAC1HDAC6HDAC8SIGMAR1SLC18A3 | |
| SCHEMBL11472209 | 0.77 | SIGMAR1 (0.68) | HDAC1HDAC6HDAC8SIGMAR1SLC18A3 | |
| SCHEMBL13519118 | 0.77 | HDAC1 (0.57) | HDAC1HDAC6HDAC8SIGMAR1SLC18A3 | |
| SCHEMBL12716195 | 0.76 | SIGMAR1 (0.59) | HDAC1HDAC6HDAC8SIGMAR1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046869-A1 | CYCLIC AMIDE DERIVATIVE | 持田製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |