Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 13/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 3/20 | 0.43 |
| ▸ | FYN | P06241 | 6/20 | 0.42 |
| ▸ | LYN | P07948 | 4/20 | 0.42 |
| ▸ | SRC | P12931 | 4/20 | 0.42 |
| ▸ | FLT3 | P36888 | 4/20 | 0.42 |
| ▸ | PTK6 | Q13882 | 4/20 | 0.42 |
| ▸ | HCK | P08631 | 3/20 | 0.42 |
| ▸ | FGR | P09769 | 3/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.42 |
| ▸ | BRAF | P15056 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15613501 | 0.91 | MAPK1 (0.46) | MAPK1CYP1A2KDM4ETP53CYP3A4 | |
| SCHEMBL16886182 | 0.89 | SRC (0.49) | MAPK1BTKRETFYNLYN | |
| SCHEMBL15613564 | 0.87 | BTK (0.49) | MAPK1CYP1A2KDM4ETP53CYP3A4 | |
| SCHEMBL16886186 | 0.87 | KDM4E (0.56) | CYP1A2KDM4EBTKPRKD3RET | |
| SCHEMBL16886166 | 0.86 | NUDT14 (0.57) | BTKSRCHCKAURKANUDT14 | |
| SCHEMBL16886190 | 0.86 | CYP1A2 (0.47) | MAPK1CYP1A2KDM4ETP53CYP3A4 | |
| SCHEMBL15613537 | 0.86 | CYP1A2 (0.47) | MAPK1CYP1A2KDM4ETP53CYP3A4 | |
| SCHEMBL15613656 | 0.85 | CYP1A2 (0.46) | MAPK1CYP1A2KDM4ETP53CYP3A4 | |
| SCHEMBL16886158 | 0.85 | SRC (0.51) | BTKRETFYNLYNSRC | |
| SCHEMBL16886202 | 0.84 | KCNH2 (0.55) | MAPK1CYP1A2KDM4ETP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796716-B2 | Selective inhibitors of Tec and Src protein kinase families | PHARMASCIENCE, INC. (CA) | 2017-10-24 | — | — | US | disclosed |
| US-20150191473-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE, INC. (CA) | 2015-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191473-A1 | PROTEIN KINASE INHIBITORS | TEC, SRC, LCK | MAPK1 159/4885CYP1A2 4734/4885KDM4E 1338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.