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NUDT14

Uridine diphosphate glucose pyrophosphatase NUDT14 · O95848 · NUDT14 on Sugi Atlas →

7,538 patent compounds predicted against NUDT14, 6,941 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL5803152 SCHEMBL5803152 0.68 3/20
SCHEMBL200349 SCHEMBL200349 0.62 3/20
SCHEMBL4825086 SCHEMBL4825086 0.56 3/20
SCHEMBL4478592 SCHEMBL4478592 0.55 3/20
SCHEMBL5812789 SCHEMBL5812789 0.53 3/20
SCHEMBL3782860 SCHEMBL3782860 0.49 3/20
SCHEMBL130529 SCHEMBL130529 1.00 2/20
SCHEMBL5804616 SCHEMBL5804616 0.93 2/20
SCHEMBL6430440 SCHEMBL6430440 0.87 2/20
SCHEMBL6430567 SCHEMBL6430567 0.85 2/20
SCHEMBL6430568 SCHEMBL6430568 0.85 2/20
SCHEMBL202187 SCHEMBL202187 0.81 2/20
SCHEMBL2631407 SCHEMBL2631407 0.78 2/20
SCHEMBL5801169 SCHEMBL5801169 0.76 2/20
SCHEMBL5803102 SCHEMBL5803102 0.76 2/20
SCHEMBL5803613 SCHEMBL5803613 0.73 2/20
SCHEMBL5803516 SCHEMBL5803516 0.73 2/20
Acetic Acid Acetic Acid (SCHEMBL4827137) 0.73 2/20
SCHEMBL3617461 SCHEMBL3617461 0.72 2/20
SCHEMBL410037 SCHEMBL410037 0.71 2/20

Clinical trials — most relevant to NUDT14 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
University of California, San Diego (UCSD) Suramin Autism Treatment-1 (SAT1) Trial PHASE1/PHASE2COMPLETED
Safety, Efficacy Evaluation of Empagliflozin Administration for Neutropenia in Glycogenosis Type 1b and G6PC3 Deficiency PHASE2UNKNOWN
Nucleoside Therapy in Patients With Telomere Biology Disorders PHASE1RECRUITING
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides PHASE1COMPLETED
Pharmacogenomic and Pharmacokinetic Safety and Cost-saving Analysis in Patients Treated With Fluoropyrimidines PHASE1COMPLETED
Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network nanRECRUITING
A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders nanRECRUITING
A Study of the Interaction Between Tumor Susceptibility Gene Glycine N-methyltransferase (GNMT) and Lung Cancer nanUNKNOWN
Identification and Characterization of Monogenic Diabetes nanCOMPLETED
Markers and Mechanisms of Macrovascular Disease in IDDM nanCOMPLETED
Investigate eNAMPT in Multiple Myeloma Biology and Establish Its Role in Disease Progression nanCOMPLETED
Thermogenic Silencer Regulatory Factors in Humans nanACTIVE_NOT_RECRUITING
Genetic Analysis of Inherited Urologic Malignant Disorders: Collection of Samples nanCOMPLETED
Genetic-specific Effects of Fructose on Liver Lipogenesis nanCOMPLETED
Dried Fruit and Postprandial Glycemia Trial nanUNKNOWN
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Hypophosphatemic Rickets in Norway nanUNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients nanRECRUITING
Dual PETOvac - Dual Time PET/CT in the Preoperative Assessment of Ovarian Cancer nanUNKNOWN
Family Blood Pressure Program - GenNet Network nanCOMPLETED
Pathophysiology of Paget's Disease of Bone nanCOMPLETED
Genetic Studies of Lysosomal Storage Disorders nanENROLLING_BY_INVITATION
Phenotype/Genotype Correlations in Neuromuscular Disorders nanCOMPLETED
Genetic Variants and Regulation of Specialized Pro-resolving Mediator nanRECRUITING
Registry of Unexplained Cardiac Arrest nanCOMPLETED
Primary Hyperoxaluria Mutation Genotyping/Phenotyping nanCOMPLETED
Germline Mutations in Pancreatic Adenocarcinoma nanCOMPLETED
Genetic Investigation of Cancer Predisposition nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a NUDT14 binder may also engage these)

ProteinNameSimilarity
Q05B60 — 0.995 Q05B60 →
Q9D142 — 0.968 Q9D142 →
Q64380 — 0.925 Q64380 →
Q5SUV1 — 0.923 Q5SUV1 →
AKR7A2 Aflatoxin B1 aldehyde reductase member 2 0.920 landscape →
Q99LB7 — 0.918 Q99LB7 →
Q0II59 — 0.917 Q0II59 →
Q5I0D5 — 0.917 Q5I0D5 →
O35083 — 0.917 O35083 →
Q95JH2 — 0.916 Q95JH2 →
O46560 — 0.916 O46560 →
Q95JH0 — 0.916 Q95JH0 →
PHOSPHO1 Phosphoethanolamine/phosphocholine phosphatase 0.916 landscape →
Q9BU20 — 0.915 Q9BU20 →
DUS2 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like 0.915 landscape →
P82197 — 0.915 P82197 →
Q8R2H9 — 0.914 Q8R2H9 →
Q3KRA9 — 0.914 Q3KRA9 →
Q99943 — 0.914 Q99943 →
A4FV98 — 0.914 A4FV98 →
Q9UL12 — 0.913 Q9UL12 →
Q0VD18 — 0.911 Q0VD18 →
Q67FW5 — 0.911 Q67FW5 →
NT5M 5'(3')-deoxyribonucleotidase, mitochondrial 0.911 landscape →
Q6WZ20 — 0.911 Q6WZ20 →
A5D7B1 — 0.910 A5D7B1 →
Q9H008 — 0.910 Q9H008 →
Q9CWS0 — 0.910 Q9CWS0 →
Q3KN66 — 0.910 Q3KN66 →
O08557 — 0.909 O08557 →