Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.67 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.67 |
| ▸ | ESR1 | P03372 | 8/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | PGR | P06401 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | AR | P10275 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | DRD1 | P21728 | 1/20 | 0.62 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5345026 | 1.00 | OPRM1 (0.67) | OPRM1SLC22A1ESR1SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL28308661 | 0.98 | OPRM1 (0.65) | OPRM1SLC22A1ESR1SLC6A2SLC6A3 | |
| SCHEMBL28309532 | 0.81 | SLC22A1 (0.66) | OPRM1SLC22A1SLC6A2SLC6A3LMNA | |
| Tapentadol SCHEMBL16267909 | 0.80 | OPRM1 (1.00) | OPRM1SLC22A1ESR1SLC6A2SLC6A3 | |
| Tapentadol SCHEMBL416917 | 0.80 | OPRM1 (1.00) | OPRM1SLC22A1ESR1SLC6A2SLC6A3 | |
| Tapentadol SCHEMBL16267561 | 0.80 | OPRM1 (1.00) | OPRM1SLC22A1ESR1SLC6A2SLC6A3 | |
| Tapentadol SCHEMBL3841350 | 0.80 | OPRM1 (1.00) | OPRM1SLC22A1ESR1SLC6A2SLC6A3 | |
| Tapentadol SCHEMBL1425181 | 0.80 | OPRM1 (1.00) | OPRM1SLC22A1ESR1SLC6A2SLC6A3 | |
| Tapentadol SCHEMBL147058 | 0.80 | OPRM1 (1.00) | OPRM1SLC22A1ESR1SLC6A2SLC6A3 | |
| Tapentadol SCHEMBL16266162 | 0.80 | OPRM1 (1.00) | OPRM1SLC22A1ESR1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105561311-B | Pharmaceutical composition comprising 3- (3- dimethylamino -1- Ethyl-2-Methyl-propyl)-phenol and NSAID | 格吕伦塔尔有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-108743549-A | The self-regulation of active pharmaceutical ingredient discharges | 阿库拉制药公司 | 2018-11-06 | — | — | CN | disclosed |
| CN-104968333-B | Self-regulated release of active pharmaceutical ingredients | 阿库拉制药公司 | 2018-07-10 | — | — | CN | disclosed |
| US-20140356314-A1 | 3-[3-(DIMETHYLAMINO)-1-ETHYL-2-METHYLPROPYL]PHENOL RESIN COMPLEX | AREVIPHARMA GMBH (DE) | 2014-12-04 | — | — | US | disclosed |
| EP-2808319-A1 | 3-[3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol resin complex | Arevipharma GmbH (DE) | 2014-12-03 | — | — | EP | disclosed |
| CN-101175482-B | Abuse-proofed dosage form | GRUENENTHAL GMBH | 2013-09-18 | — | — | CN | disclosed |
| EP-2611425-A1 | TAMPER RESISTANT DOSAGE FORM COMPRISING AN ANIONIC POLYMER | Grünenthal GmbH (DE) | 2013-07-10 | — | — | EP | disclosed |
| EP-2595971-A1 | SALTS OR CO-CRYSTALS OF 3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL | Grünenthal GmbH (DE) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012028318-A1 | TAMPER RESISTANT DOSAGE FORM COMPRISING AN ANIONIC POLYMER | Grünenthal GmbH (DE) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012010316-A1 | SALTS OR CO-CRYSTALS OF 3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL | Grünenthal GmbH (DE) | 2012-01-26 | — | — | WO | disclosed |