SSU72 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL18289705	0.61	3/20
SCHEMBL18281591	0.60	3/20
SCHEMBL18291877	0.60	3/20
SCHEMBL18281617	0.59	3/20
SCHEMBL20281609	0.59	3/20
SCHEMBL18281579	0.59	3/20
SCHEMBL18289706	0.57	3/20
SCHEMBL18289745	0.56	3/20
SCHEMBL18289748	0.56	3/20
SCHEMBL18289710	0.56	3/20
SCHEMBL6939608	0.56	3/20
SCHEMBL18281622	0.55	3/20
SCHEMBL18281593	0.54	3/20
SCHEMBL18281588	0.53	3/20
SCHEMBL20281612	0.52	3/20
SCHEMBL18289889	0.51	3/20
SCHEMBL11630026	0.49	3/20
SCHEMBL18281601	0.48	3/20
SCHEMBL20281610	0.47	3/20
SCHEMBL18289704	0.46	3/20

Clinical trials — most relevant to SSU72 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma	PHASE1/PHASE2	COMPLETED
Effect of PAE Hydrogel Loaded With tRF-ASO-Exo on Patients With Diabetic Ocular Surface Diseases	PHASE2	NOT_YET_RECRUITING
Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft TIssue Sarcoma After Pre-treatment Failure	PHASE2	COMPLETED
Safety and Efficacy Study of Small Interfering RNA Molecule (Cand5) to Treat Diabetic Macular Edema	PHASE2	COMPLETED
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome	PHASE1	COMPLETED
Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors	PHASE1	COMPLETED
Imetelstat for Children With Refractory or Recurrent Solid Tumors and Lymphoma	PHASE1	WITHDRAWN
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck	PHASE1	COMPLETED
A Phase I Trial of SHR3162 in Subjects With Advanced Solid Tumors	PHASE1	COMPLETED
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors	nan	COMPLETED
DNA Methylation and Perioperative Pain Treatment	nan	COMPLETED
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia	nan	NOT_YET_RECRUITING
Impact of Seasonal Malaria Chemoprevention on Immunity Against Malaria Among Children in Northern Benin	nan	COMPLETED
DNA Damage & Repair Proteins In Patients With Atherosclerotic Coronary Artery Disease	nan	COMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
Trichomonas Vaginalis Genotyping in Upper Egypt	nan	UNKNOWN
Mitoquines in COPD	nan	UNKNOWN
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Investigations Into ISCU Myopathy or Iron Sulfur Scaffold U Protein Myopathy	nan	COMPLETED
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population	nan	COMPLETED
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis	nan	COMPLETED
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide	nan	RECRUITING
Characterization of Transcriptional Regulators of Ghrelin Hormone Which Causes Genetic Obesity	nan	COMPLETED
Modeling DNA Diversity in Reverse Cholesterol Transport	nan	COMPLETED
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress	nan	WITHDRAWN
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma	nan	COMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics	nan	UNKNOWN
Role of Sorcin and Annexin A3 in Breast Cancer Patients	nan	UNKNOWN
Spironolactone and XPB-1 Integrity in the TFIIH Complex	nan	ENROLLING_BY_INVITATION
Maximizing Mechanisms of Muscle Hypertrophy to Combat Sarcopenia in Older Adults	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a SSU72 binder may also engage these)

Protein	Name	Similarity
Q5ZJQ7	—	1.000	Q5ZJQ7 →
Q17QI2	—	1.000	Q17QI2 →
Q4KLK9	—	1.000	Q4KLK9 →
Q9CY97	—	1.000	Q9CY97 →
Q6NRQ7	—	0.954	Q6NRQ7 →
Q13888	—	0.954	Q13888 →
Q6P1K8	—	0.948	Q6P1K8 →
Q2TBV5	—	0.947	Q2TBV5 →
F1LTR1	—	0.945	F1LTR1 →
Q5SP67	—	0.943	Q5SP67 →
Q5F398	—	0.940	Q5F398 →
Q9JIB4	—	0.939	Q9JIB4 →
PAICS	Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase	0.939	landscape →
Q5R532	—	0.937	Q5R532 →
Q4R9A8	—	0.935	Q4R9A8 →
Q7L5Y9	—	0.935	Q7L5Y9 →
A0JN27	—	0.935	A0JN27 →
Q8C6G8	—	0.934	Q8C6G8 →
Q4VC33	—	0.930	Q4VC33 →
Q28D01	—	0.930	Q28D01 →
Q5RKJ1	—	0.930	Q5RKJ1 →
WDR26	WD repeat-containing protein 26	0.927	landscape →
COPS2	COP9 signalosome complex subunit 2	0.926	landscape →
Q5RB59	—	0.926	Q5RB59 →
P61203	—	0.926	P61203 →
Q9WV18	—	0.925	Q9WV18 →
Q8BTQ0	—	0.923	Q8BTQ0 →
Q9Z0U4	—	0.923	Q9Z0U4 →
Q91854	—	0.923	Q91854 →
Q6IQT4	—	0.923	Q6IQT4 →