Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16877014 | 1.00 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL16888284 | 1.00 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL16891806 | 0.95 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL16891716 | 0.95 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL16880558 | 0.91 | RORC (0.92) | RORCNR1I2 | |
| SCHEMBL18204941 | 0.91 | RORC (0.83) | RORCNR1I2 | |
| SCHEMBL16888296 | 0.91 | RORC (0.83) | RORCNR1I2 | |
| SCHEMBL16877049 | 0.91 | RORC (0.83) | RORCNR1I2 | |
| SCHEMBL16891798 | 0.89 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL16891760 | 0.89 | RORC (1.00) | RORCNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708253-B2 | Cyclohexyl sulfone RORγ modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-07-18 | — | — | US | disclosed |
| US-9708253-B2 | Cyclohexyl sulfone RORγ modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-07-18 | — | — | US | disclosed |
| WO-2015103507-A1 | CYCLOHEXYL SULFONE RORϒ MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-07-09 | — | — | WO | disclosed |