Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 20/20 | 0.82 |
| ▸ | ACVRL1 | P37023 | 12/20 | 0.68 |
| ▸ | ACVR1B | P36896 | 14/20 | 0.66 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.66 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16879606 | 0.91 | TGFBR1 (1.00) | TGFBR1ACVRL1ACVR1BACVR1BMPR1A | |
| SCHEMBL16879403 | 0.90 | TGFBR1 (0.78) | TGFBR1ACVRL1ACVR1BACVR1BMPR1A | |
| SCHEMBL16879258 | 0.82 | TGFBR1 (0.75) | TGFBR1ACVRL1ACVR1BACVR1BMPR1A | |
| SCHEMBL16879528 | 0.82 | TGFBR1 (0.71) | TGFBR1ACVRL1ACVR1BACVR1BMPR1A | |
| SCHEMBL16879626 | 0.82 | TGFBR1 (0.76) | TGFBR1ACVRL1ACVR1BACVR1 | |
| SCHEMBL16879512 | 0.81 | TGFBR1 (1.00) | TGFBR1ACVRL1ACVR1BACVR1BMPR1A | |
| SCHEMBL25954763 | 0.81 | TGFBR1 (0.87) | TGFBR1ACVRL1ACVR1BACVR1BMPR1A | |
| SCHEMBL16879134 | 0.81 | TGFBR1 (1.00) | TGFBR1ACVRL1ACVR1BACVR1BMPR1A | |
| SCHEMBL31060771 | 0.81 | TGFBR1 (1.00) | TGFBR1ACVRL1ACVR1BACVR1BMPR1A | |
| SCHEMBL16879561 | 0.81 | TGFBR1 (0.72) | TGFBR1ACVRL1ACVR1BACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3089971-B1 | COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2020-07-29 | — | — | EP | disclosed |
| WO-2015103355-A1 | COMPOUNDS AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-07-09 | — | — | WO | disclosed |