Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 18/20 | 0.82 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16888997 | 0.90 | NR1D1 (1.00) | NR1D1 | |
| SCHEMBL16888936 | 0.90 | NR1D1 (1.00) | NR1D1HCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL16888962 | 0.90 | NR1D1 (0.85) | NR1D1HCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL16888933 | 0.90 | NR1D1 (1.00) | NR1D1HCRTR1HCRTR2 | |
| SCHEMBL16889094 | 0.90 | NR1D1 (1.00) | NR1D1HCRTR1HCRTR2 | |
| SCHEMBL16888957 | 0.88 | NR1D1 (0.85) | NR1D1HCRTR1HCRTR2 | |
| SCHEMBL16888986 | 0.88 | NR1D1 (1.00) | NR1D1HCRTR1HCRTR2 | |
| SCHEMBL16888893 | 0.88 | NR1D1 (0.84) | NR1D1HCRTR1HCRTR2 | |
| SCHEMBL16888928 | 0.88 | NR1D1 (1.00) | NR1D1HCRTR1HCRTR2 | |
| SCHEMBL16888990 | 0.87 | NR1D1 (0.82) | NR1D1HCRTR1HCRTR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015103527-A1 | MODULATORS OF REV-ERB | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-07-09 | — | — | WO | disclosed |