Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GUSB | P08236 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18235987 | 0.84 | POLB (0.38) | POLBKMT2ASRCALDH1A1NOTUM | |
| SCHEMBL15257805 | 0.82 | MAOA (0.43) | POLBKMT2ASRCALDH1A1NOTUM | |
| SCHEMBL13878324 | 0.81 | CYP19A1 (0.51) | POLBKMT2AALDH1A1 | |
| SCHEMBL25836730 | 0.81 | POLB (0.56) | POLBKMT2AALDH1A1HDAC1 | |
| SCHEMBL25836729 | 0.81 | SRC (0.38) | POLBKMT2ASRCALDH1A1HSP90AB1 | |
| SCHEMBL7963203 | 0.78 | NOTUM (0.49) | NOTUM | |
| SCHEMBL15495572 | 0.78 | SRC (0.36) | POLBKMT2ASRCALDH1A1NPC1 | |
| SCHEMBL24276636 | 0.77 | HDAC1 (0.48) | ALDH1A1HDAC1 | |
| SCHEMBL13437076 | 0.77 | FOLH1 (0.46) | POLBKMT2AALDH1A1HDAC1 | |
| SCHEMBL24276661 | 0.76 | EPHX2 (0.47) | ALDH1A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015100498-A1 | COMPOSITIONS AND METHODS FOR IMAGING CANCER | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2015-07-09 | — | — | WO | disclosed |