SCHEMBL1689386

SCHEMBL1689386

[CH2]C(O)C(=C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL822667 0.76
SCHEMBL15676 0.75
SCHEMBL210425 0.75
SCHEMBL212534 0.75
SCHEMBL716194 0.73
SCHEMBL14193188 0.73
SCHEMBL7564616 0.73 ALDH1A1 (0.31)
SCHEMBL2546600 0.73
SCHEMBL20523270 0.73
SCHEMBL19028 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240180932-A1 SUBSTITUTED RESORCYLIC ACID COMPOUNDS IN THE MANAGEMENT OF AGEING AND RELATED DISORDERS NESTLE SA (CH) 2024-06-06 US claimed
EP-4313017-A1 SUBSTITUTED RESORCYLIC ACID COMPOUNDS IN THE MANAGEMENT OF AGEING AND RELATED DISORDERS Société des Produits Nestlé S.A. (CH) 2024-02-07 EP claimed
US-20240010589-A1 SUBSTITUTED RESORCINOL COMPOUNDS AS AMPK ACTIVATORS, COMPOSITIONS, METHODS AND USES THEREOF NESTLE SA (CH) 2024-01-11 US claimed
US-20230414638-A1 SUBSTITUTED RESORCYLIC ACID COMPOUNDS AS AMPK ACTIVATOR AND USES THEREOF NESTLE SA (CH) 2023-12-28 US claimed
CN-116981452-A Substituted resorcinol compounds for the management of aging and related disorders 雀巢产品有限公司 2023-10-31 CN claimed
CN-116761791-A Substituted resorcinol compounds as AMPK activators and uses thereof 雀巢产品有限公司 2023-09-15 CN claimed
CN-116744911-A Substituted resorcinol compounds as AMPK activators, compositions, methods and uses thereof 雀巢产品有限公司 2023-09-12 CN claimed
US-20230026772-A1 DIBENZOPYRAN AMPK ACTIVATOR COMPOUNDS, COMPOSITIONS, METHODS AND USES THEREOF SOCIETE DES PRODUITS NESTLE S.A. (CH) 2023-01-26 US claimed
CN-114727979-A Dibenzopyran AMPK activator compounds, compositions, methods and uses thereof 雀巢产品有限公司 2022-07-08 CN claimed
WO-2021105075-A1 DIBENZOPYRAN AMPK ACTIVATOR COMPOUNDS, COMPOSITIONS, METHODS AND USES THEREOF Société des Produits Nestlé S.A. (CH) 2021-06-03 WO claimed
CN-102276621-A Compounds isolated from gamboge resin and derivatives thereof, and pharmaceutical compositions comprising these compounds and derivatives 2011-12-14 CN claimed
CN-101384540-A Novel nutraceutical and pharmaceutical compositions and use thereof for the treatment, co-treatment or prevention of inflammatory disorders DSM IP ASSETS BV (NL) 2009-03-11 CN claimed
US-20080319071-A1 Novel Nutraceutical and Pharmaceutical Compositions and Use Thereof for the Treatment, Co-Treatment or Prevention of Inflammatory Disorders DSM IP ASSETS B.V. (NL) 2008-12-25 US claimed
EP-1984317-A1 NOVEL NUTRACEUTICAL AND PHARMACEUTICAL COMPOSITIONS AND USE THEREOF FOR THE TREATMENT, CO-TREATMENT OR PREVENTION OF INFLAMMATORY DISORDERS DSMIP Assets B.V. (NL) 2008-10-29 EP claimed
WO-2007093387-A1 NOVEL NUTRACEUTICAL AND PHARMACEUTICAL COMPOSITIONS AND USE THEREOF FOR THE TREATMENT, CO-TREATMENT OR PREVENTION OF INFLAMMATORY DISORDERS DSM IP ASSETS B.V. (NL) 2007-08-23 WO claimed
US-20240180932-A1 SUBSTITUTED RESORCYLIC ACID COMPOUNDS IN THE MANAGEMENT OF AGEING AND RELATED DISORDERS NESTLE SA (CH) 2024-06-06 US disclosed
CN-118047788-A Isopentenyl phenolic compound, and preparation method and application thereof 中国医药工业研究总院有限公司 2024-05-17 CN disclosed
US-20080319071-A1 Novel Nutraceutical and Pharmaceutical Compositions and Use Thereof for the Treatment, Co-Treatment or Prevention of Inflammatory Disorders DSM IP ASSETS B.V. (NL) 2008-12-25 US disclosed
US-20070092551-A1 Therapeutic agent TAKARA BIO INC. (JP) 2007-04-26 US disclosed
EP-1623704-A1 THERAPEUTIC AGENT TAKARA BIO INC. (JP) 2006-02-08 EP disclosed