Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | TAS2R31 | P59538 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | ROR1 | Q01973 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31322130 | 1.00 | ALDH1A1 (0.73) | ALDH1A1ABCG2KDM4ECYP3A4HPGD | |
| SCHEMBL5857357 | 0.86 | ALDH1A1 (0.76) | ALDH1A1ABCG2KDM4ECYP3A4HPGD | |
| SCHEMBL18106040 | 0.86 | ALDH1A1 (0.83) | ALDH1A1ABCG2KDM4ECYP3A4HPGD | |
| SCHEMBL30319723 | 0.86 | ALDH1A1 (0.83) | ALDH1A1ABCG2KDM4ECYP3A4HPGD | |
| SCHEMBL4826267 | 0.86 | ALDH1A1 (0.83) | ALDH1A1ABCG2KDM4ECYP3A4HPGD | |
| SCHEMBL31452750 | 0.85 | TAS2R31 (0.62) | ALDH1A1ABCG2KDM4ECYP3A4HPGD | |
| SCHEMBL16894635 | 0.85 | ALDH1A1 (0.63) | ALDH1A1ABCG2KDM4ECYP3A4HPGD | |
| Dimethylpinocembrin SCHEMBL2879027 | 0.85 | ABCG2 (1.00) | ALDH1A1ABCG2KDM4ECYP3A4HPGD | |
| SCHEMBL12067056 | 0.84 | ALDH1A1 (0.80) | ALDH1A1ABCG2KDM4ECYP3A4HPGD | |
| SCHEMBL12067071 | 0.83 | ALDH1A1 (0.71) | ALDH1A1ABCG2KDM4ECYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669003-B2 | Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs | JIN YONGRI (CN) | 2017-06-06 | — | — | US | claimed |
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | JIN YONGRI (CN) | 2015-07-16 | — | — | US | claimed |
| US-9669003-B2 | Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs | JIN YONGRI (CN) | 2017-06-06 | — | — | US | disclosed |
| CN-103705502-B | Application of flavonoid compound in treating inflammatory diseases | 江苏省中国科学院植物研究所 | 2017-05-24 | — | — | CN | disclosed |
| CN-103705502-B | Application of flavonoid compound in treating inflammatory diseases | 江苏省中国科学院植物研究所 | 2017-05-24 | — | — | CN | disclosed |
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | JIN YONGRI (CN) | 2015-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | CYP2D6, GATAD2A, CYP3A43 | ALDH1A1 668/4885ABCG2 98/4885KDM4E 437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.