Geranin A

Geranin A

SCHEMBL1689479

Oc1ccc([C@H]2Oc3c(c(O)cc4c3[C@@H]3c5c(O)cc(O)cc5O[C@](c5ccc(O)cc5)(O4)[C@H]3O)C[C@H]2O)cc1

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VEGFA P15692 3/20 0.89
PGF P49763 3/20 0.89
FLT1 P17948 2/20 0.89
PRKAA2 P54646 1/20 0.81
PRKD3 O94806 3/20 0.72
PRKCG P05129 3/20 0.72
PRKCB P05771 3/20 0.72
PRKCA P17252 3/20 0.72
PRKCH P24723 3/20 0.72
PRKCI P41743 3/20 0.72
PRKCE Q02156 3/20 0.72
PRKCQ Q04759 3/20 0.72
PRKCZ Q05513 3/20 0.72
PRKCD Q05655 3/20 0.72
PRKD1 Q15139 3/20 0.72
PDE4D Q08499 1/20 0.64
PTGS1 P23219 2/20 0.59
MMP2 P08253 4/20 0.57
MMP9 P14780 4/20 0.57
ALPL P05186 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Geranin A SCHEMBL31186795 1.00 VEGFA (0.89) VEGFAPGFFLT1PRKAA2PRKD3
Geranin A SCHEMBL29554993 1.00 VEGFA (0.89) VEGFAPGFFLT1PRKAA2PRKD3
Geranin D SCHEMBL30414509 0.97 VEGFA (0.85) VEGFAPGFFLT1PRKAA2PRKD3
Selligueain A SCHEMBL29511856 0.94 PRKD3 (0.83) VEGFAPGFFLT1PRKAA2PRKD3
Selligueain A SCHEMBL29363150 0.94 PRKD3 (0.83) VEGFAPGFFLT1PRKAA2PRKD3
Selligueain A SCHEMBL23699013 0.94 PRKD3 (0.83) VEGFAPGFFLT1PRKAA2PRKD3
Proanthocyanidin A2 SCHEMBL14273881 0.90 VEGFA (1.00) VEGFAPGFFLT1PRKAA2PRKD3
Proanthocyanidin A2 SCHEMBL18350173 0.90 VEGFA (1.00) VEGFAPGFFLT1PRKAA2PRKD3
Proanthocyanidin A2 SCHEMBL15394643 0.90 VEGFA (1.00) VEGFAPGFFLT1PRKAA2PRKD3
Proanthocyanidin A1 SCHEMBL1689429 0.90 VEGFA (1.00) VEGFAPGFFLT1PRKAA2PRKD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210146006-A1 COMPOSITE CONTAINING COLLAGEN AND ELASTIN AS A DERMAL EXPANDER AND TISSUE FILLER TRUELASTIN LABORATORIES, INC. 2021-05-20 US claimed
US-10583218-B2 Composite containing collagen and elastin as a dermal expander and tissue filler HANCOCK JAFFE LABORATORIES AESTHETICS, INC. (US) 2020-03-10 US claimed
US-20120010146-A1 COMPOSITE CONTAINING COLLAGEN AND ELASTIN AS A DERMAL EXPANDER AND TISSUE FILLER HANCOCK JAFFE LABORATORIES, INC. (US) 2012-01-12 US claimed
WO-2010053918-A1 COMPOSITE CONTAINING COLLAGEN AND ELASTIN AS A DERMAL EXPANDER AND TISSUE FILLER HANCOCK JAFFE LABORATORIES, INC. (US) 2010-05-14 WO claimed
JP-58154585-A None JP disclosed
US-20220291237-A1 Gene Expression Inflammatory Age and Its Uses Edifice Health, Inc. (US) 2022-09-15 US disclosed
US-20210146006-A1 COMPOSITE CONTAINING COLLAGEN AND ELASTIN AS A DERMAL EXPANDER AND TISSUE FILLER TRUELASTIN LABORATORIES, INC. 2021-05-20 US disclosed
US-10583218-B2 Composite containing collagen and elastin as a dermal expander and tissue filler HANCOCK JAFFE LABORATORIES AESTHETICS, INC. (US) 2020-03-10 US disclosed
US-20160243280-A1 COMPOSITE CONTAINING COLLAGEN AND ELASTIN AS A DERMAL EXPANDER AND TISSUE FILLER TRUELASTIN LABORATORIES, INC. 2016-08-25 US disclosed
US-9248165-B2 Composite containing collagen and elastin as a dermal expander and tissue filler HANCOCK-JAFFE LABORATORIES, INC. (US) 2016-02-02 US disclosed
US-20120010146-A1 COMPOSITE CONTAINING COLLAGEN AND ELASTIN AS A DERMAL EXPANDER AND TISSUE FILLER HANCOCK JAFFE LABORATORIES, INC. (US) 2012-01-12 US disclosed
WO-2010053918-A1 COMPOSITE CONTAINING COLLAGEN AND ELASTIN AS A DERMAL EXPANDER AND TISSUE FILLER HANCOCK JAFFE LABORATORIES, INC. (US) 2010-05-14 WO disclosed
JP-S58154585-A NOVEL FLAVONOIDS SUNTORY LTD 1983-09-14 JP disclosed