SCHEMBL168957

SCHEMBL168957

NCCCCC(O)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.60
GPR84 Q9NQS5 3/20 0.58
RNPEP Q9H4A4 1/20 0.58
FFAR1 O14842 1/20 0.58
CPB2 Q96IY4 4/20 0.52
TET2 Q6N021 3/20 0.48
KDM4A O75164 2/20 0.48
KDM4C Q9H3R0 2/20 0.48
KDM2A Q9Y2K7 2/20 0.48
TET3 O43151 1/20 0.48
FOLH1 Q04609 1/20 0.44
CYP2D6 P10635 1/20 0.44
NFKB1 P19838 1/20 0.44
BLM P54132 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
PLG P00747 1/20 0.42
LMNA P02545 1/20 0.42
THRB P10828 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2981272 1.00 GSR (0.60) GSRGPR84RNPEPFFAR1CPB2
SCHEMBL17262908 1.00 GSR (0.60) GSRGPR84RNPEPFFAR1CPB2
SCHEMBL7027171 0.98 GPR84 (0.61) GSRGPR84RNPEPFFAR1CPB2
SCHEMBL7874857 0.98 GPR84 (0.61) GSRGPR84RNPEPFFAR1CPB2
SCHEMBL7925235 0.98 GPR84 (0.61) GSRGPR84RNPEPFFAR1CPB2
SCHEMBL4820853 0.92
SCHEMBL3347601 0.92
SCHEMBL4819961 0.92
SCHEMBL28089828 0.88 GPR84 (0.81) GSRGPR84FFAR1MEN1ALDH1A1
SCHEMBL11651698 0.87 GPR84 (0.71) GSRGPR84FFAR1TET2KDM4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1428 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331804-A1 NANOPARTICLE SYSTEMS TO STIMULATE AND MAINTAIN IMMUNE SYSTEM RESPONSIVENESS AT TREATMENT SITES FRED HUTCHINSON CANCER CENTER (US) 2023-10-19 US claimed
US-20230013253-A1 COMPOSTIONS AND METHODS FOR NUCLEIC ACID TRANSFECTION USING CATIONIC POLYMERS AND STABILIZERS PFIZER INC. 2023-01-19 US claimed
US-11180538-B2 Combinatorial gene construct and non-viral delivery for anti-obesity UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2021-11-23 US claimed
WO-2021138600-A1 NANOPARTICLE SYSTEMS TO STIMULATE AND MAINTAIN IMMUNE SYSTEM RESPONSIVENESS AT TREATMENT SITES FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2021-07-08 WO claimed
WO-2021124152-A1 COMPOSITIONS AND METHODS FOR NUCLEIC ACID TRANSFECTION USING CATIONIC POLYMERS AND STABILIZERS PFIZER INC. (US) 2021-06-24 WO claimed
US-20210128485-A1 NANOPARTICLES FOR GENE EXPRESSION AND USES THEREOF FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2021-05-06 US claimed
EP-3787996-A1 NANOPARTICLES FOR GENE EXPRESSION AND USES THEREOF Fred Hutchinson Cancer Research Center (US) 2021-03-10 EP claimed
US-20200247864-A1 COMBINATORIAL GENE CONSTRUCT AND NON-VIRAL DELIVERY FOR ANTI-OBESITY UNIVERSITY OF UTAH 2020-08-06 US claimed
US-20200140844-A1 CRISPR NANOCOMPLEX FOR NONVIRAL GENOME EDITING AND METHOD FOR PREPARING THE SAME KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2020-05-07 US claimed
EP-3442585-A1 COMPOSITIONS AND METHODS TO PROGRAM THERAPEUTIC CELLS USING TARGETED NUCLEIC ACID NANOCARRIERS Fred Hutchinson Cancer Research Center (US) 2019-02-20 EP claimed
US-20030124368-A1 Methods of making decomposable thin films of polyelectrolytes and uses thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-07-03 US claimed
WO-2003035716-A1 METHODS OF MAKING DECOMPOSABLE THIN FILMS OF POLYELECTROLYTES AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2003-05-01 WO claimed
WO-2002042426-A2 CARRIER SYSTEM FOR SPECIFIC ARTERY WALL GENE DELIVERY UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2002-05-30 WO claimed
EP-1117720-A4 POLYESTER ANALOGUE OF POLY-L-LYSINE AS A SOLUBLE, BIODEGRADABLE GENE DELIVERY CARRIER EXPRESSION GENETICS INC (US) 2001-11-14 EP claimed
CN-1313873-A Polyester analogus of poly-L-Lysine as a soluble, biodegradable gene delivery carrier EXPRESSION GENETICS INC (US) 2001-09-19 CN claimed
EP-1117720-A1 POLYESTER ANALOGUE OF POLY-L-LYSINE AS A SOLUBLE, BIODEGRADABLE GENE DELIVERY CARRIER Expression Genetics, Inc. (US) 2001-07-25 EP claimed
US-6217912-B1 POLY((4-AMINOBUTYL-)GLYCOLIC ACID EXPRESSION GENETICS, INC. 2001-04-17 US claimed
WO-2000002950-A9 POLYESTER ANALOGUE OF POLY-L-LYSINE AS A SOLUBLE, BIODEGRADABLE GENE DELIVERY CARRIER EXPRESSION GENETICS INC (US) 2000-07-20 WO claimed
WO-2000002950-A1 POLYESTER ANALOGUE OF POLY-L-LYSINE AS A SOLUBLE, BIODEGRADABLE GENE DELIVERY CARRIER EXPRESSION GENETICS, INC. (US) 2000-01-20 WO claimed
US-4363815-A Alpha hydroxyacids, alpha ketoacids and their use in treating skin conditions YU RUEY J 1982-12-14 US claimed