Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 10/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | TOP1 | P11387 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16904616 | 0.93 | CYP2C9 (0.53) | NQO1TNKSTOP1GAARAB9A | |
| SCHEMBL16904614 | 0.92 | CYP2C9 (0.43) | NQO1TNKSTOP1GAARAB9A | |
| SCHEMBL16904605 | 0.87 | CYP2C9 (0.58) | NQO1TNKSTOP1GAARAB9A | |
| SCHEMBL16904609 | 0.85 | CYP2C9 (0.47) | NQO1TNKSTOP1GAARAB9A | |
| SCHEMBL20355820 | 0.83 | TNKS (0.39) | NQO1TNKSTOP1GAARAB9A | |
| SCHEMBL1649142 | 0.83 | NQO1 (0.73) | NQO1TOP1CYP2C9CRHBPCASP7 | |
| SCHEMBL18465488 | 0.82 | NQO1 (0.51) | NQO1TOP1GAACYP2C9CRHBP | |
| SCHEMBL21169024 | 0.77 | KMT2A (0.39) | NQO1TNKSRAB9ACYP2C9L3MBTL1 | |
| SCHEMBL4960881 | 0.74 | NQO1 (0.60) | NQO1TOP1CYP2C9CRHBPCASP7 | |
| SCHEMBL1649800 | 0.72 | MAOA (0.52) | NQO1GAACYP2C9CRHBPCASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220175777-A1 | Inhibitors of Multidrug Resistance Transporter P-Glycoprotein | SOUTHERN METHODIST UNIVERSITY | 2022-06-09 | — | — | US | disclosed |
| US-11234978-B2 | Inhibitors of multidrug resistance transporter P-glycoprotein | SOUTHERN METHODIST UNIVERSITY (US) | 2022-02-01 | — | — | US | disclosed |
| US-11234978-B2 | Inhibitors of multidrug resistance transporter P-glycoprotein | SOUTHERN METHODIST UNIVERSITY (US) | 2022-02-01 | — | — | US | disclosed |
| US-11013739-B2 | Inhibitors of multidrug resistance transporter p-glycoprotein | SOUTHERN METHODIST UNIVERSITY (US) | 2021-05-25 | — | — | US | disclosed |
| US-11013739-B2 | Inhibitors of multidrug resistance transporter p-glycoprotein | SOUTHERN METHODIST UNIVERSITY (US) | 2021-05-25 | — | — | US | disclosed |
| US-10898485-B2 | Inhibitors of multidrug resistance transporter p-glycoprotein | SOUTHERN METHODIST UNIVERSITY (US) | 2021-01-26 | — | — | US | disclosed |
| US-20200138816-A1 | Inhibitors of Multidrug Resistance Transporter P-Glycoprotein | SOUTHERN METHODIST UNIVERSITY | 2020-05-07 | — | — | US | disclosed |
| US-20200138816-A1 | Inhibitors of Multidrug Resistance Transporter P-Glycoprotein | SOUTHERN METHODIST UNIVERSITY | 2020-05-07 | — | — | US | disclosed |
| US-20200069687-A1 | Inhibitors of Multidrug Resistance Transporter P-Glycoprotein | SOUTHERN METHODIST UNIVERSITY | 2020-03-05 | — | — | US | disclosed |
| US-20200069687-A1 | Inhibitors of Multidrug Resistance Transporter P-Glycoprotein | SOUTHERN METHODIST UNIVERSITY | 2020-03-05 | — | — | US | disclosed |
| US-10172855-B2 | Inhibitors of multidrug resistance transporter P-glycoprotein | SOUTHERN METHODIST UNIVERSITY (US) | 2019-01-08 | — | — | US | disclosed |
| US-10172855-B2 | Inhibitors of multidrug resistance transporter P-glycoprotein | SOUTHERN METHODIST UNIVERSITY (US) | 2019-01-08 | — | — | US | disclosed |
| US-20180185366-A1 | Inhibitors of Multidrug Resistance Transporter P-Glycoprotein | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-07-05 | — | — | US | disclosed |
| US-20180185366-A1 | Inhibitors of Multidrug Resistance Transporter P-Glycoprotein | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-07-05 | — | — | US | disclosed |
| US-20180185366-A1 | Inhibitors of Multidrug Resistance Transporter P-Glycoprotein | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-07-05 | — | — | US | disclosed |
| US-20170128447-A1 | Inhibitors of Multidrug Resistance Transporter P-Glycoprotein | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-05-11 | — | — | US | disclosed |
| US-20170128447-A1 | Inhibitors of Multidrug Resistance Transporter P-Glycoprotein | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-05-11 | — | — | US | disclosed |
| US-20170128447-A1 | Inhibitors of Multidrug Resistance Transporter P-Glycoprotein | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-05-11 | — | — | US | disclosed |
| US-9561227-B2 | Inhibitors of multidrug resistance transporter P-glycoprotein | SOUTHERN METHODIST UNIVERSITY (US) | 2017-02-07 | — | — | US | disclosed |
| US-20150196560-A1 | Inhibitors of Multidrug Resistance Transporter P-Glycoprotein | SOUTHERN METHODIST UNIVERSITY | 2015-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200069687-A1 | Inhibitors of Multidrug Resistance Transporter P-Glycoprotein | ABCC1, ABCB1, SLC47A2 | NQO1 1026/4885TNKS 3364/4885TOP1 719/4885 |
| US-20170128447-A1 | Inhibitors of Multidrug Resistance Transporter P-Glycoprotein | ABCC1, ABCB1, SLC47A2 | NQO1 1026/4885TNKS 3364/4885TOP1 719/4885 |
| US-11234978-B2 | Inhibitors of multidrug resistance transporter P-glycoprotein | ABCC1, ABCB1, SLC47A2 | NQO1 1026/4885TNKS 3364/4885TOP1 719/4885 |
| US-20200138816-A1 | Inhibitors of Multidrug Resistance Transporter P-Glycoprotein | ABCC1, ABCB1, SLC47A2 | NQO1 1026/4885TNKS 3364/4885TOP1 719/4885 |
| US-20180185366-A1 | Inhibitors of Multidrug Resistance Transporter P-Glycoprotein | ABCC1, ABCB1, SLC47A2 | NQO1 1026/4885TNKS 3364/4885TOP1 719/4885 |
| US-20150196560-A1 | Inhibitors of Multidrug Resistance Transporter P-Glycoprotein | ABCC1, ABCB1, SLC47A2 | NQO1 1026/4885TNKS 3364/4885TOP1 719/4885 |
| US-10172855-B2 | Inhibitors of multidrug resistance transporter P-glycoprotein | ABCC1, ABCB1, SLC47A2 | NQO1 1026/4885TNKS 3364/4885TOP1 719/4885 |
| US-11013739-B2 | Inhibitors of multidrug resistance transporter p-glycoprotein | ABCC1, ABCB1, SLC47A2 | NQO1 1026/4885TNKS 3364/4885TOP1 719/4885 |
| US-10898485-B2 | Inhibitors of multidrug resistance transporter p-glycoprotein | ABCC1, ABCB1, SLC47A2 | NQO1 1026/4885TNKS 3364/4885TOP1 719/4885 |
| US-20220175777-A1 | Inhibitors of Multidrug Resistance Transporter P-Glycoprotein | ABCC1, ABCB1, SLC47A2 | NQO1 1026/4885TNKS 3364/4885TOP1 719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.