Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 7/20 | 0.35 |
| ▸ | MMP9 | P14780 | 3/20 | 0.35 |
| ▸ | MMP13 | P45452 | 3/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27182598 | 0.70 | GAA (0.55) | GAAMCOLN3MAPTHTTKDM4E | |
| SCHEMBL27182591 | 0.67 | GAA (0.60) | GAAMCOLN3MAPTHTTKDM4E | |
| SCHEMBL2884788 | 0.67 | GAA (0.55) | GAAMCOLN3MAPTHTTKDM4E | |
| SCHEMBL3392545 | 0.67 | HTR7 (0.46) | POLBGAAMCOLN3MAPTHTT | |
| SCHEMBL27182526 | 0.66 | GAA (0.58) | GAAMCOLN3MAPTHTTKDM4E | |
| SCHEMBL3936342 | 0.64 | GAA (0.53) | GAAMCOLN3MAPTHTTKDM4E | |
| Urea SCHEMBL28572479 | 0.64 | GAA (0.50) | GAAMCOLN3MAPTHTTKDM4E | |
| SCHEMBL9772270 | 0.63 | GAA (0.53) | GAAMCOLN3MAPTHTTKDM4E | |
| SCHEMBL27183144 | 0.62 | NPC1 (0.49) | GAAMCOLN3MAPTHTTKDM4E | |
| SCHEMBL5374534 | 0.61 | POLB (0.35) | POLBGAANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015104343-A1 | NEW ANTIFIBRINOLYTIC COMPOUNDS | PROYECTO DE BIOMEDICINA CIMA, S.L. (ES) | 2015-07-16 | — | — | WO | claimed |
| WO-2015104343-A1 | NEW ANTIFIBRINOLYTIC COMPOUNDS | PROYECTO DE BIOMEDICINA CIMA, S.L. (ES) | 2015-07-16 | — | — | WO | disclosed |