Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.45 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.45 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.43 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.43 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ANTXR2 | P58335 | 2/20 | 0.42 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HMGCR | P04035 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695145 | 0.99 | PTPN1 (0.48) | PTPN1PTPN2PTPN6PTPN11LGALS3 | |
| SCHEMBL5356500 | 0.99 | PTPN1 (0.48) | PTPN1PTPN2PTPN6PTPN11LGALS3 | |
| SCHEMBL5695036 | 0.99 | PTPN1 (0.48) | PTPN1PTPN2PTPN6PTPN11LGALS3 | |
| SCHEMBL5356505 | 0.99 | PTPN1 (0.48) | PTPN1PTPN2PTPN6PTPN11LGALS3 | |
| SCHEMBL5695045 | 0.99 | PTPN1 (0.48) | PTPN1PTPN2PTPN6PTPN11LGALS3 | |
| SCHEMBL5695029 | 0.99 | PTPN1 (0.48) | PTPN1PTPN2PTPN6PTPN11LGALS3 | |
| SCHEMBL14428922 | 0.91 | PTPN1 (0.56) | PTPN1PTPN2PTPN11USP2MEN1 | |
| SCHEMBL22455860 | 0.91 | PTPN1 (0.56) | PTPN1PTPN2PTPN11USP2MEN1 | |
| SCHEMBL20730007 | 0.91 | PTPN1 (0.56) | PTPN1PTPN2PTPN11USP2MEN1 | |
| SCHEMBL13271795 | 0.91 | PTPN1 (0.56) | PTPN1PTPN2PTPN11USP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3094639-A1 | METHOD FOR OPTIMIZING POST-TRANSLATIONAL MODIFICATIONS ON RECOMBINANT PROTEINS | Leszcyniecka, Magdalena (US) | 2016-11-23 | — | — | EP | disclosed |
| WO-2015106276-A1 | METHOD FOR OPTIMIZING POST-TRANSLATIONAL MODIFICATIONS ON RECOMBINANT PROTEINS | LESZCYNIECKA MAGDALENA (US) | 2015-07-16 | — | — | WO | disclosed |