Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16899041 | 0.91 | IRAK4 (0.54) | IRAK4 | |
| SCHEMBL18207945 | 0.91 | IRAK4 (0.49) | IRAK4 | |
| SCHEMBL29986084 | 0.91 | IRAK4 (0.55) | IRAK4 | |
| SCHEMBL16899016 | 0.91 | IRAK4 (0.55) | IRAK4 | |
| Hydrochloric Acid SCHEMBL16898978 | 0.90 | IRAK4 (0.54) | IRAK4 | |
| SCHEMBL16899252 | 0.90 | IRAK4 (0.54) | IRAK4 | |
| SCHEMBL16899141 | 0.89 | IRAK4 (0.54) | IRAK4 | |
| SCHEMBL16899159 | 0.89 | IRAK4 (0.48) | IRAK4 | |
| SCHEMBL18207947 | 0.89 | IRAK4 (0.49) | IRAK4 | |
| Hydrochloric Acid SCHEMBL16898967 | 0.89 | IRAK4 (0.54) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092226-A1 | INDAZOLE COMPOUNDS AS IRAK4 INHIBITORS | Aurigene Discovery Technologies Limited (IN) | 2016-11-16 | — | — | EP | disclosed |
| WO-2015104662-A1 | INDAZOLE COMPOUNDS AS IRAK4 INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2015-07-16 | — | — | WO | disclosed |