Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.55 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16899016 | 1.00 | IRAK4 (0.55) | IRAK4IRAK1 | |
| Hydrochloric Acid SCHEMBL16898978 | 0.99 | IRAK4 (0.54) | IRAK4IRAK1 | |
| SCHEMBL16899041 | 0.94 | IRAK4 (0.54) | IRAK4 | |
| SCHEMBL16899141 | 0.93 | IRAK4 (0.54) | IRAK4 | |
| Hypochlorous Acid SCHEMBL20787534 | 0.93 | IRAK4 (0.54) | IRAK4 | |
| Hydrochloric Acid SCHEMBL16898967 | 0.93 | IRAK4 (0.54) | IRAK4IRAK1 | |
| SCHEMBL16899252 | 0.92 | IRAK4 (0.54) | IRAK4 | |
| SCHEMBL16899267 | 0.91 | IRAK4 (0.49) | IRAK4 | |
| SCHEMBL18207945 | 0.91 | IRAK4 (0.49) | IRAK4 | |
| SCHEMBL16899259 | 0.91 | IRAK4 (0.51) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4319750-A1 | COMBINATION THERAPIES FOR THE TREATMENT OF CANCER | Curis, Inc. (US) | 2024-02-14 | — | — | EP | claimed |
| WO-2022216379-A1 | COMBINATION THERAPIES FOR THE TREATMENT OF CANCER | CURIS, INC. (US) | 2022-10-13 | — | — | WO | claimed |