Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16898644 | 0.86 | USP2 (0.38) | TLR8EPHX2CHRM2CHRM1CHRM4 | |
| SCHEMBL16898400 | 0.86 | USP2 (0.38) | TLR8EPHX2CHRM2CHRM1CHRM4 | |
| SCHEMBL16898465 | 0.86 | USP2 (0.38) | TLR8EPHX2CHRM2CHRM1CHRM4 | |
| SCHEMBL16898385 | 0.86 | USP2 (0.38) | TLR8EPHX2CHRM2CHRM1CHRM4 | |
| SCHEMBL16898492 | 0.85 | USP2 (0.39) | TLR8EPHX2CHRM2CHRM1CHRM4 | |
| SCHEMBL16899905 | 0.82 | TLR8 (0.34) | TLR8RXFP1EPHX2CHRM2CHRM1 | |
| SCHEMBL16899895 | 0.81 | CHRM2 (0.35) | TLR8RXFP1EPHX2CHRM2CHRM1 | |
| SCHEMBL16899904 | 0.78 | MMP2 (0.42) | — | |
| SCHEMBL16899915 | 0.78 | MMP2 (0.42) | — | |
| SCHEMBL16906830 | 0.78 | USP2 (0.38) | EPHX2CHRM2CHRM1CHRM4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015106294-A1 | BIVALENT BCR-ABL TYROSINE KINASE LIGANDS, AND METHODS OF USING SAME | COFERON,INC. (US) | 2015-07-16 | — | — | WO | disclosed |