SCHEMBL1689992

SCHEMBL1689992

CCCCCCCCCCC/C=C\CCCCCCCCCOP(=O)(O)C(CC)C[N+](C)(C)C

nearest known ligand 0.55

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 11/20 0.55
LPAR2 Q9HBW0 7/20 0.55
LPAR1 Q92633 7/20 0.55
P2RY10 O00398 3/20 0.47
SLC6A5 Q9Y345 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1689951 0.85 LPAR3 (0.56) LPAR3LPAR2LPAR1P2RY10SLC6A5
SCHEMBL53526 0.81 LPAR3 (0.57) LPAR3LPAR2LPAR1P2RY10
SCHEMBL53780 0.81 LPAR3 (0.57) LPAR3LPAR2LPAR1P2RY10
SCHEMBL53844 0.81 LPAR3 (0.57) LPAR3LPAR2LPAR1P2RY10
SCHEMBL52774 0.81 LPAR3 (0.57) LPAR3LPAR2LPAR1P2RY10
SCHEMBL53469 0.81 LPAR3 (0.57) LPAR3LPAR2LPAR1P2RY10
SCHEMBL52233 0.81 LPAR3 (0.57) LPAR3LPAR2LPAR1P2RY10
SCHEMBL53710 0.81 LPAR3 (0.57) LPAR3LPAR2LPAR1P2RY10
SCHEMBL53039 0.81 LPAR3 (0.57) LPAR3LPAR2LPAR1P2RY10
SCHEMBL53145 0.81 LPAR3 (0.57) LPAR3LPAR2LPAR1P2RY10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8497388-B2 Phospholipid-analogous compounds MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN. E.V. (DE) 2013-07-30 US disclosed
US-20120009246-A1 PHOSPHOLIPID-ANALOGOUS COMPOUNDS MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2012-01-12 US disclosed
US-7939683-B2 Phospholipid-analogous compounds MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2011-05-10 US disclosed
US-20100183705-A1 PHOSPHOLIPID-ANALOGOUS COMPOUNDS Max-Planck-Gesellschaft zur Förderung du Wissenschaften e.V. (DE) 2010-07-22 US disclosed
US-6828453-B2 Phospholipid-analogous compounds MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V (DE) 2004-12-07 US disclosed
US-20030198663-A1 Phospholipid-analogous compounds EIBL HANS-JORG (DE) 2003-10-23 US disclosed
EP-1019417-B1 PHOSPHOLIPID ANALOGUE COMPOUNDS MAX PLANCK GESELLSCHAFT (DE) 2002-10-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120009246-A1 PHOSPHOLIPID-ANALOGOUS COMPOUNDS SGMS1, DEGS1, SGMS2 LPAR3 55/4885LPAR2 39/4885LPAR1 30/4885
US-20100183705-A1 PHOSPHOLIPID-ANALOGOUS COMPOUNDS SGMS1, DEGS1, SGMS2 LPAR3 30/4885LPAR2 12/4885LPAR1 11/4885
US-20030198663-A1 Phospholipid-analogous compounds SGMS1, PHOSPHO1, DEGS1 LPAR3 47/4885LPAR2 12/4885LPAR1 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.