Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 18/20 | 0.46 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.46 |
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16900038 | 0.82 | PARP1 (0.35) | PDE9A | |
| SCHEMBL6338878 | 0.82 | PDE9A (0.60) | PDE9APDE1C | |
| SCHEMBL16900048 | 0.80 | PDE9A (0.48) | PDE9APDE1C | |
| SCHEMBL16900063 | 0.77 | PDE9A (0.37) | PDE9APDE1C | |
| SCHEMBL16900052 | 0.76 | PDE9A (0.58) | PDE9APDE1C | |
| SCHEMBL16900037 | 0.76 | PDE9A (0.41) | PDE9APDE1C | |
| SCHEMBL16900034 | 0.76 | PDE9A (0.38) | PDE9APDE1C | |
| SCHEMBL16900035 | 0.76 | L3MBTL1 (0.41) | PDE9A | |
| SCHEMBL16900036 | 0.74 | PDE9A (0.41) | PDE9APDE1C | |
| SCHEMBL16900031 | 0.72 | PDE9A (0.39) | PDE9APDE1CSPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9079905-B2 | Compounds for the treatment of CNS disorders | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-07-14 | — | — | US | disclosed |