Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.42 |
| ▸ | IDH1 | O75874 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16900307 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MAPTHTR2AHTR2CSCN9A | |
| SCHEMBL16020167 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MAPTGRM7HTR2AHTR2C | |
| SCHEMBL14698954 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPTGRM7HTR2AHTR2C | |
| SCHEMBL14698157 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPTGRM7HTR2AHTR2C | |
| SCHEMBL364560 | 0.78 | MAPT (0.65) | ALDH1A1MAPTGRM7HTR2AHTR2C | |
| SCHEMBL2639848 | 0.76 | ALDH1A1 (0.58) | ALDH1A1MAPTGRM7HTR2AHTR2C | |
| SCHEMBL14697904 | 0.75 | ALDH1A1 (0.57) | ALDH1A1MAPTGRM7HTR2AHTR2C | |
| Benzene SCHEMBL27840008 | 0.74 | ALDH1A1 (0.60) | ALDH1A1MAPTGRM7HTR2AHTR2C | |
| SCHEMBL15646149 | 0.74 | ALDH1A1 (0.52) | ALDH1A1MAPTGRM7HTR2AHTR2C | |
| SCHEMBL15031547 | 0.71 | ALDH1A1 (0.56) | ALDH1A1MAPTGRM7HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9079902-B2 | Heteroaryl sodium channel inhibitors | AMGEN INC. (US) | 2015-07-14 | — | — | US | disclosed |