Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 20/20 | 0.70 |
| ▸ | EDNRB | P24530 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1259727 | 0.93 | EDNRA (0.69) | EDNRAEDNRB | |
| SCHEMBL1258645 | 0.90 | EDNRA (0.62) | EDNRAEDNRB | |
| SCHEMBL8324802 | 0.89 | EDNRA (0.58) | EDNRAEDNRB | |
| SCHEMBL617288 | 0.89 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL29770411 | 0.89 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL8328060 | 0.89 | EDNRA (0.63) | EDNRA | |
| SCHEMBL5686011 | 0.89 | EDNRA (0.71) | EDNRAEDNRB | |
| SCHEMBL8326059 | 0.89 | EDNRA (0.64) | EDNRAEDNRB | |
| SCHEMBL625550 | 0.89 | EDNRA (0.71) | EDNRAEDNRB | |
| SCHEMBL5499789 | 0.88 | EDNRA (0.63) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2550256-B1 | PROCESS FOR THE PREPARATION OF BOSENTAN | LESVI LABORATORIOS SL (ES) | 2015-07-15 | — | — | EP | disclosed |