SCHEMBL16900730

SCHEMBL16900730

NC(N)NCCC[C@H](N)C(=O)I

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ DPP7 Q9UHL4 2/20 0.35
▸ OTC P00480 1/20 0.35
▸ GSR P00390 1/20 0.33
▸ SLC15A1 P46059 1/20 0.32
▸ GNAI3 P08754 1/20 0.31
▸ GNAO1 P09471 1/20 0.31
▸ GNAI1 P63096 1/20 0.31
▸ ANPEP P15144 2/20 0.31
▸ RNPEP Q9H4A4 2/20 0.31
▸ DNPEP Q9ULA0 1/20 0.31
▸ ARG1 P05089 3/20 0.31
▸ ARG2 P78540 3/20 0.31
▸ NOD1 Q9Y239 1/20 0.31
▸ DDAH1 O94760 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15292001 0.83 DPP7 (0.37) DPP7OTCGSRSLC15A1GNAI3
SCHEMBL13337953 0.81 GSR (0.54) OTCGSRARG1ARG2DDAH1
SCHEMBL17274213 0.81 GSR (0.54) OTCGSRARG1ARG2DDAH1
SCHEMBL16602952 0.81 DPP7 (0.36) DPP7OTCGSRSLC15A1GNAI3
SCHEMBL16602446 0.80 DPP7 (0.33) DPP7OTCGSRSLC15A1
SCHEMBL18819441 0.79 DPP7 (0.39) DPP7OTCGSRSLC15A1GNAI3
SCHEMBL16167872 0.79 DPP7 (0.35) DPP7OTCGSRSLC15A1GNAI3
SCHEMBL11947672 0.79 DPP7 (0.39) DPP7OTCGSRSLC15A1GNAI3
SCHEMBL14878828 0.79 DPP7 (0.39) DPP7OTCGSRSLC15A1GNAI3
SCHEMBL13580090 0.78 DPP7 (0.33) DPP7OTCSLC15A1ANPEPRNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2132315-B1 REOVIRUSES HAVING MODIFIED SEQUENCES ONCOLYTICS BIOTECH INC (CA) 2015-07-15 — — EP disclosed
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