SCHEMBL16901059

SCHEMBL16901059

C1=Cc2c(c3cc(-c4ccc5c(c4)c4ccccc4n5-c4cc(-c5ccccc5)cc(-c5ccccc5)c4)ccc3n2-c2ccccc2)CC1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
TSPO P30536 1/20 0.33
HDAC4 P56524 1/20 0.31
KMT2A Q03164 2/20 0.30
IL1R1 P14778 1/20 0.30
PTGER4 P35408 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26239028 1.00 L3MBTL1 (0.39) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL21583501 0.97 ATM (0.35) L3MBTL1KDM4EATMTSPOALDH1A1
SCHEMBL26156841 0.94 L3MBTL1 (0.40) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL29343543 0.94 L3MBTL1 (0.42) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL17012686 0.94 ATM (0.39) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL23203991 0.93 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL26196489 0.93 ATM (0.38) L3MBTL1KDM4EATMTSPOALDH1A1
SCHEMBL19791137 0.93 KDM4E (0.40) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL18903134 0.93 L3MBTL1 (0.45) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL21923270 0.93 ATM (0.38) L3MBTL1KDM4EATMTSPOHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2894157-A1 Condensed cyclic compound and organic light-emitting device including the same Samsung Electronics Co., Ltd (KR) 2015-07-15 EP disclosed