Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.55 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | NNMT | P40261 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10015138 | 0.93 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9ACDK5CDK5R1 | |
| SCHEMBL18786347 | 0.90 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9ACDK5CDK5R1 | |
| SCHEMBL12588185 | 0.89 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9ACDK5CDK5R1 | |
| SCHEMBL27389762 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9ACDK5CDK5R1 | |
| SCHEMBL26551793 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9ACDK5CDK5R1 | |
| SCHEMBL13499099 | 0.80 | RAB9A (0.57) | SMN1; SMN2NPC1RAB9ACDK5CDK5R1 | |
| SCHEMBL18135013 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9ACDK5CDK5R1 | |
| SCHEMBL16450938 | 0.79 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9ACDK5CDK5R1 | |
| SCHEMBL10025164 | 0.78 | BAZ2B (0.47) | SMN1; SMN2NPC1RAB9ACDK5CDK5R1 | |
| SCHEMBL22644579 | 0.76 | RAB9A (0.54) | SMN1; SMN2NPC1RAB9ACDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298736-B1 | Hydrazine-based and carbonyl-based bifunctional crosslinking reagents | SOLULINK INC (US) | 2015-07-15 | — | — | EP | disclosed |