Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | HTR1D | P28221 | 3/20 | 0.36 |
| ▸ | HTR1B | P28222 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18317138 | 0.87 | BRD4 (0.41) | L3MBTL1FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL16905973 | 0.84 | L3MBTL1 (0.46) | L3MBTL1FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL16897775 | 0.79 | BRD4 (0.44) | L3MBTL1CYP2C9HTR1AHTR1DHTR1B | |
| SCHEMBL18317114 | 0.78 | BRD4 (0.41) | L3MBTL1CYP2C9CYP3A4POLBMAPT | |
| SCHEMBL18326362 | 0.77 | L3MBTL1 (0.46) | L3MBTL1CYP2C9HTR1AHTR1DHTR1B | |
| SCHEMBL16896942 | 0.74 | L3MBTL1 (0.44) | L3MBTL1CYP2C9CYP3A4USP2BRD4 | |
| SCHEMBL16896794 | 0.73 | BRD4 (0.43) | L3MBTL1CYP2C9CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL16896893 | 0.72 | BRD4 (0.44) | L3MBTL1CYP2C9CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL18326396 | 0.71 | L3MBTL1 (0.43) | L3MBTL1USP2BRD4PIK3CG | |
| SCHEMBL18581628 | 0.71 | L3MBTL1 (0.44) | L3MBTL1CYP2C9CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015104653-A1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS BROMODOMAIN INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2015-07-16 | — | — | WO | disclosed |