Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 3/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.35 |
| ▸ | ITGAL | P20701 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRB2 | P62993 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6620751 | 0.86 | ITGB2 (0.47) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL6620753 | 0.86 | ITGB2 (0.47) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL19463542 | 0.86 | ITGB2 (0.47) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL11401620 | 0.83 | ITGB2 (0.33) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL5777336 | 0.83 | ECE1 (0.44) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL6623611 | 0.82 | FOLH1 (0.35) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL6623613 | 0.82 | FOLH1 (0.35) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL17697188 | 0.81 | PTPN1 (0.37) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL10993372 | 0.80 | SMN1; SMN2 (0.35) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL7349775 | 0.80 | ECE1 (0.46) | ECE1ITGB2ICAM1ITGALCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015106200-A2 | DIPEPTIDES AS INHIBITORS OF HUMAN IMMUNOPROTEASOMES | CORNELL UNIVERSITY (US) | 2015-07-16 | — | — | WO | disclosed |