Methacrylic Acid

Methacrylic Acid

SCHEMBL16908400

C1CO1.C=C(C)C(=O)O.C=CC(=O)OCCCC.CC(=CC=Cc1ccccc1)C(=O)O

nearest known ligand 0.48

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.48
HPGD P15428 2/20 0.44
TSHR P16473 2/20 0.44
TDP1 Q9NUW8 2/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 5/20 0.42
LMNA P02545 3/20 0.42
POLB P06746 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.37
APP P05067 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
BCHE P06276 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL760166 0.92 KDM4E (0.55) KDM4EHPGDTSHRTDP1MEN1
SCHEMBL3469074 0.88 KDM4E (0.53) KDM4EHPGDTSHRTDP1MEN1
Water SCHEMBL4244899 0.88 KDM4E (0.53) KDM4EHPGDTSHRTDP1MEN1
Oxirane SCHEMBL51272 0.84 KDM4E (0.53) KDM4EHPGDTSHRTDP1MEN1
Methacrylic Acid SCHEMBL51273 0.84 TSHR (0.44) KDM4EHPGDTSHRTDP1MEN1
SCHEMBL4243868 0.83 KDM4E (0.60) KDM4EHPGDTSHRTDP1MEN1
Methacrylic Acid SCHEMBL2318559 0.82 AKR1C3 (0.45) KDM4ETDP1KMT2AALDH1A1LMNA
Juarezic Acid SCHEMBL2878619 0.82 HPGD (0.49) KDM4EHPGDTSHRTDP1MEN1
SCHEMBL30023403 0.81 TSHR (0.63) KDM4EHPGDTSHRTDP1MEN1
Methacrylic Acid SCHEMBL2529223 0.81 TSHR (0.67) HPGDTSHRALDH1A1LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2896996-A1 Static charge image developing toner and image forming method, image forming apparatus, and process cartridge using same Ricoh Company, Ltd. (JP) 2015-07-22 EP disclosed