Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 10/20 | 0.64 |
| ▸ | KIT | P10721 | 8/20 | 0.64 |
| ▸ | SRC | P12931 | 1/20 | 0.60 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.59 |
| ▸ | KDR | P35968 | 2/20 | 0.59 |
| ▸ | CSF1R | P07333 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4110676 | 0.91 | KIT (0.78) | ABL1KITFGFR1KDRCSF1R | |
| SCHEMBL16755327 | 0.87 | KIT (0.81) | ABL1KITSRCFGFR1KDR | |
| SCHEMBL28054441 | 0.83 | ABL1 (0.69) | ABL1KITSRC | |
| SCHEMBL4099939 | 0.83 | KIT (0.67) | ABL1KITFGFR1KDRCSF1R | |
| SCHEMBL24626425 | 0.82 | KIT (0.75) | ABL1KITSRCFGFR1KDR | |
| SCHEMBL15774143 | 0.82 | ABL1 (0.85) | ABL1KITFGFR1 | |
| SCHEMBL29674969 | 0.82 | KIT (0.80) | ABL1KITSRC | |
| SCHEMBL16755287 | 0.82 | KIT (0.80) | ABL1KITSRC | |
| SCHEMBL16755306 | 0.82 | ABL1 (0.63) | ABL1KITSRCFGFR1 | |
| SCHEMBL29675075 | 0.82 | KIT (0.74) | ABL1KITSRCFGFR1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9255107-B2 | Heteroaryl alkyne compound and use thereof | NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) | 2016-02-09 | — | — | US | disclosed |
| US-20150299202-A1 | HETEROARYL ALKYNE COMPOUND AND USE THEREOF | NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) | 2015-10-22 | — | — | US | disclosed |
| EP-2927232-A1 | HETEROARYL ALKYNE COMPOUND AND APPLICATION THEREOF | Nanjing Sanhome Pharmaceutical Co., Ltd. (CN) | 2015-10-07 | — | — | EP | disclosed |
| EP-2896620-A1 | ALKYNYL HETEROAROMATIC RING COMPOUND AND APPLICATION THEREOF | Nanjing Sanhome Pharmaceutical Co., Ltd. (CN) | 2015-07-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299202-A1 | HETEROARYL ALKYNE COMPOUND AND USE THEREOF | ABL1, ALK, ABL2 | ABL1 1/4885KIT 163/4885SRC 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.