Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 5/20 | 0.80 |
| ▸ | SRC | P12931 | 2/20 | 0.65 |
| ▸ | BRAF | P15056 | 11/20 | 0.64 |
| ▸ | ABL1 | P00519 | 2/20 | 0.62 |
| ▸ | EGFR | P00533 | 9/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16755287 | 1.00 | KIT (0.80) | KITSRCBRAFABL1EGFR | |
| SCHEMBL30080656 | 0.89 | KIT (1.00) | KITBRAFABL1EGFR | |
| SCHEMBL588917 | 0.89 | KIT (0.93) | KITBRAFEGFR | |
| SCHEMBL588975 | 0.89 | KIT (1.00) | KITBRAFABL1EGFR | |
| SCHEMBL29493482 | 0.89 | KIT (1.00) | KITBRAFABL1EGFR | |
| SCHEMBL16755327 | 0.85 | KIT (0.81) | KITSRCBRAFABL1 | |
| SCHEMBL30904911 | 0.85 | KIT (0.71) | KITSRCBRAFABL1EGFR | |
| SCHEMBL20912769 | 0.85 | KIT (0.71) | KITSRCBRAFABL1EGFR | |
| SCHEMBL19986829 | 0.84 | KIT (0.68) | KITSRCBRAFABL1EGFR | |
| SCHEMBL31053459 | 0.82 | KIT (0.66) | KITSRCBRAFABL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149855-A1 | HETEROARYL-ETHYNYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-07-14 | — | — | WO | disclosed |